{"title":"坚持治疗炎症性肠病特别关注临床药师的重要性:系统回顾。","authors":"Faria Sayed, Mark Andrew Ainsworth","doi":"10.1111/bcpt.70125","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>The prevalence of inflammatory bowel disease (IBD) is increasing. While several studies have shown that incorporating a clinical pharmacist into patient care can improve quality of life, evidence specifically addressing their role in IBD management remains limited.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>This study aimed to systematically review the evidence on treatment adherence in IBD, with a focus on the potential role of clinical pharmacist counselling to improve medication adherence.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Three databases (PubMed, MEDLINE and Embase) were searched to identify relevant literature, using keywords derived from the PICO model.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Seven full-text articles met the inclusion criteria. Three of these reported that pharmacist involvement had a positive effect on treatment adherence in patients with IBD. Furthermore, two studies reported that pharmacist involvement in treatment improved disease activity. Patients' perceptions of pharmacist involvement were generally positive, particularly after receiving information about pharmacist services and education. Finally, studies also indicate that pharmacists require greater knowledge of IBD to provide optimal care.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Although the available literature is limited, it indicates that involving clinical pharmacists in IBD treatment may have a positive impact—improving medication adherence and enhancing disease control.</p>\n </section>\n </div>","PeriodicalId":8733,"journal":{"name":"Basic & Clinical Pharmacology & Toxicology","volume":"137 5","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486352/pdf/","citationCount":"0","resultStr":"{\"title\":\"Adherence in the Treatment of Inflammatory Bowel Disease With Particular Focus on the Importance of the Clinical Pharmacist: A Systematic Review\",\"authors\":\"Faria Sayed, Mark Andrew Ainsworth\",\"doi\":\"10.1111/bcpt.70125\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>The prevalence of inflammatory bowel disease (IBD) is increasing. While several studies have shown that incorporating a clinical pharmacist into patient care can improve quality of life, evidence specifically addressing their role in IBD management remains limited.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>This study aimed to systematically review the evidence on treatment adherence in IBD, with a focus on the potential role of clinical pharmacist counselling to improve medication adherence.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Three databases (PubMed, MEDLINE and Embase) were searched to identify relevant literature, using keywords derived from the PICO model.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Seven full-text articles met the inclusion criteria. Three of these reported that pharmacist involvement had a positive effect on treatment adherence in patients with IBD. Furthermore, two studies reported that pharmacist involvement in treatment improved disease activity. Patients' perceptions of pharmacist involvement were generally positive, particularly after receiving information about pharmacist services and education. Finally, studies also indicate that pharmacists require greater knowledge of IBD to provide optimal care.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Although the available literature is limited, it indicates that involving clinical pharmacists in IBD treatment may have a positive impact—improving medication adherence and enhancing disease control.</p>\\n </section>\\n </div>\",\"PeriodicalId\":8733,\"journal\":{\"name\":\"Basic & Clinical Pharmacology & Toxicology\",\"volume\":\"137 5\",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486352/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Basic & Clinical Pharmacology & Toxicology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/bcpt.70125\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Basic & Clinical Pharmacology & Toxicology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/bcpt.70125","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Adherence in the Treatment of Inflammatory Bowel Disease With Particular Focus on the Importance of the Clinical Pharmacist: A Systematic Review
Background
The prevalence of inflammatory bowel disease (IBD) is increasing. While several studies have shown that incorporating a clinical pharmacist into patient care can improve quality of life, evidence specifically addressing their role in IBD management remains limited.
Objectives
This study aimed to systematically review the evidence on treatment adherence in IBD, with a focus on the potential role of clinical pharmacist counselling to improve medication adherence.
Methods
Three databases (PubMed, MEDLINE and Embase) were searched to identify relevant literature, using keywords derived from the PICO model.
Results
Seven full-text articles met the inclusion criteria. Three of these reported that pharmacist involvement had a positive effect on treatment adherence in patients with IBD. Furthermore, two studies reported that pharmacist involvement in treatment improved disease activity. Patients' perceptions of pharmacist involvement were generally positive, particularly after receiving information about pharmacist services and education. Finally, studies also indicate that pharmacists require greater knowledge of IBD to provide optimal care.
Conclusion
Although the available literature is limited, it indicates that involving clinical pharmacists in IBD treatment may have a positive impact—improving medication adherence and enhancing disease control.
期刊介绍:
Basic & Clinical Pharmacology and Toxicology is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.