Recent Development in Synthesis and Anticonvulsant Activity of Promising Schiff Base Derivatives

One of the most common neurological conditions in the world, epilepsy, increases a person's risk of dying young by three times when compared to the general population. This has led to the development of new antiepileptic drugs, although safety and potency are concerns. Additionally, Schiff base derivatives (commonly referred to as imines or azomethines) are a significant player in the medical treatment of epilepsy. Apart from being essential linkers and intermediates, this adaptable moiety also acts as a basic scaffold in the building of compounds with biological activity. Numerous Schiff base derivatives have been shown to regulate and cure neurological illnesses by blocking enzymes, receptors, and other targets. To cure epilepsy, researchers are concentrating on creating novel derivatives based on Schiff bases since they serve as a linker for various pharmacophores. Thus, this study sheds light on the current therapeutic expansion of derivatives based on Schiff bases as well as their synthesis schemes, all of which will assist researchers in creating effective prospective antiepileptic medications with advantageous pharmacological action.