Feifei Lv, Xin Zhang, Liang Wang, Shaodan Li, Fagen Li
{"title":"逍遥散联合八珍汤治疗乳腺癌术后失眠的临床疗效观察","authors":"Feifei Lv, Xin Zhang, Liang Wang, Shaodan Li, Fagen Li","doi":"10.1002/msp2.70016","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>This study aimed to evaluate the effects of Xiaoyao San combined with Bazhen Decoction on insomnia in patients following breast cancer surgery.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A total of 86 patients experiencing insomnia after breast cancer surgery were randomly assigned to either the treatment group or the control group. The treatment group received Xiaoyao San combined with Bazhen Decoction, while the control group was treated with estazolam tablets. The treatment duration was 4 weeks. Pittsburgh Sleep Quality Index (PSQI) scores were assessed before and after treatment. The overall efficacy and incidence of adverse reactions were compared between the two groups.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>PSQI scores in both groups significantly decreased after treatment (<i>p</i> < 0.05). Total effective rate in the treatment group (93.02%) was higher than that in the control group (86.05%), although the difference was not statistically significant (<i>p</i> > 0.05). The incidence of adverse reactions in the treatment group (4.65%) was significantly lower than that in the control group (20.93%) (<i>p</i> < 0.05).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Xiaoyao San combined with Bazhen Decoction can effectively improve sleep quality in patients with insomnia following breast cancer surgery, demonstrating good clinical efficacy and fewer adverse reactions. Further studies are needed to confirm these findings and explore broader clinical applications.</p>\n </section>\n </div>","PeriodicalId":100882,"journal":{"name":"Malignancy Spectrum","volume":"2 3","pages":"145-150"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msp2.70016","citationCount":"0","resultStr":"{\"title\":\"Clinical efficacy of Xiaoyao San combined with Bazhen Decoction in the treatment of insomnia in postoperative breast cancer patients\",\"authors\":\"Feifei Lv, Xin Zhang, Liang Wang, Shaodan Li, Fagen Li\",\"doi\":\"10.1002/msp2.70016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>This study aimed to evaluate the effects of Xiaoyao San combined with Bazhen Decoction on insomnia in patients following breast cancer surgery.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A total of 86 patients experiencing insomnia after breast cancer surgery were randomly assigned to either the treatment group or the control group. The treatment group received Xiaoyao San combined with Bazhen Decoction, while the control group was treated with estazolam tablets. The treatment duration was 4 weeks. Pittsburgh Sleep Quality Index (PSQI) scores were assessed before and after treatment. The overall efficacy and incidence of adverse reactions were compared between the two groups.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>PSQI scores in both groups significantly decreased after treatment (<i>p</i> < 0.05). Total effective rate in the treatment group (93.02%) was higher than that in the control group (86.05%), although the difference was not statistically significant (<i>p</i> > 0.05). The incidence of adverse reactions in the treatment group (4.65%) was significantly lower than that in the control group (20.93%) (<i>p</i> < 0.05).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Xiaoyao San combined with Bazhen Decoction can effectively improve sleep quality in patients with insomnia following breast cancer surgery, demonstrating good clinical efficacy and fewer adverse reactions. Further studies are needed to confirm these findings and explore broader clinical applications.</p>\\n </section>\\n </div>\",\"PeriodicalId\":100882,\"journal\":{\"name\":\"Malignancy Spectrum\",\"volume\":\"2 3\",\"pages\":\"145-150\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/msp2.70016\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Malignancy Spectrum\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/msp2.70016\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malignancy Spectrum","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/msp2.70016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Clinical efficacy of Xiaoyao San combined with Bazhen Decoction in the treatment of insomnia in postoperative breast cancer patients
Objective
This study aimed to evaluate the effects of Xiaoyao San combined with Bazhen Decoction on insomnia in patients following breast cancer surgery.
Methods
A total of 86 patients experiencing insomnia after breast cancer surgery were randomly assigned to either the treatment group or the control group. The treatment group received Xiaoyao San combined with Bazhen Decoction, while the control group was treated with estazolam tablets. The treatment duration was 4 weeks. Pittsburgh Sleep Quality Index (PSQI) scores were assessed before and after treatment. The overall efficacy and incidence of adverse reactions were compared between the two groups.
Results
PSQI scores in both groups significantly decreased after treatment (p < 0.05). Total effective rate in the treatment group (93.02%) was higher than that in the control group (86.05%), although the difference was not statistically significant (p > 0.05). The incidence of adverse reactions in the treatment group (4.65%) was significantly lower than that in the control group (20.93%) (p < 0.05).
Conclusion
Xiaoyao San combined with Bazhen Decoction can effectively improve sleep quality in patients with insomnia following breast cancer surgery, demonstrating good clinical efficacy and fewer adverse reactions. Further studies are needed to confirm these findings and explore broader clinical applications.
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