髋关节射频消融后患者报告的结果:一项回顾性研究

Melissa Schwartz , Alejandra Cardenas-Rojas , Michael Suarez , Anna Megenhardt , Ahmed Khawer , Annie Yang , Eric Muneio , Pranamya Suri , Akhil Chhatre
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引用次数: 0

摘要

主要由骨关节炎引起的慢性髋关节疼痛是一种普遍的疾病,对许多人来说,它会显著降低生活质量。射频消融术(RFA)是一种很有前途的微创治疗方法,针对髋关节周围的感觉神经提供持续的缓解。然而,选择合适的患者和预测结果的指南仍然不清楚。目的本研究旨在评估髋关节射频消融术后患者报告的疼痛结果,并确定影响治疗反应的术前患者因素。方法本回顾性研究于2019年8月至2024年8月在某三级学术中心进行,收集了2019年8月至2024年8月期间接受闭孔神经和股神经关节分支单侧或双侧RFA的患者的数据。收集的信息包括人口统计、骨关节炎严重程度、阿片类药物和抗抑郁药物的使用,以及手术前后疼痛的数字评定量表(NRS)评分。主要结局指标为NRS评分前后差异,考虑NRS改善≥2分和疼痛减轻≥50%的临床意义。次要结果包括使用患者整体变化印象(PGIC)量表测量的患者感知。进行Logistic回归分析以确定治疗成功的预测因素。结果共54例患者(64例手术),女性居多(64.8%),平均年龄68岁,BMI 31.43 kg/m2。术后NRS中位数显著降低2.5个点(p < 0.001)。总体而言,56.25%的患者达到临床意义≥2点的NRS降低,43.75%的患者疼痛减轻≥50%。大约66%的患者报告PGIC评分有所改善。应答者疼痛缓解的平均持续时间为6个月。术前未使用阿片类药物的患者(OR = 0.24, p = 0.027)和BMI较高的患者(p = 0.04)的预后明显较好。结论髋关节RFA在减轻慢性髋关节疼痛患者疼痛水平和改善患者报告的预后方面具有潜力。较好的结果明显与术前阿片类药物的使用和较高的BMI有关。需要进一步的研究来完善患者选择指南并评估手术后的功能改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patient-reported outcomes following radiofrequency ablation of the hip: a retrospective study

Background

Chronic hip pain, primarily caused by osteoarthritis, is a prevalent condition that significantly reduces quality of life for many individuals. Radiofrequency ablation (RFA) has emerged as a promising, minimally invasive treatment targeting sensory nerves around the hip joint to provide sustained relief. However, guidelines for selecting suitable patients and predicting outcomes remain unclear.

Objective

This study aimed to evaluate patient-reported pain outcomes following hip RFA and to identify pre-procedure patient factors influencing treatment response.

Methods

In this retrospective study conducted at a tertiary academic center, data was collected from patients undergoing unilateral or bilateral RFA of the articular branches of the obturator and femoral nerves between August 2019 and August 2024. Information collected included demographics, osteoarthritis severity, opioid and antidepressant use, and pre- and post-procedure numeric rating scale (NRS) scores for pain. Primary outcome measures were pre-post difference NRS score, considering clinically meaningful a ≥2-point improvement in NRS and ≥50 % pain reduction. Secondary outcomes included patient perceptions measured using the Patient Global Impression of Change (PGIC) scale. Logistic regression analysis was conducted to identify predictors of treatment success.

Results

Fifty-four patients (64 procedures) participated, predominantly female (64.8 %), with an average age of 68 years old and BMI of 31.43 kg/m2. A significant median reduction of 2.5 points in NRS was reported post-procedure (p < 0.001). Overall, 56.25 % of patients achieved a clinically meaningful ≥2-point NRS reduction, and 43.75 % experienced ≥50 % pain reduction. Approximately 66 % of patients reported improvement on the PGIC scale. The average duration of pain relief among responders was six months. Patients without pre-procedure opioid use (OR = 0.24, p = 0.027) and those with higher BMI (p = 0.04) had significantly better outcomes.

Conclusion

Hip RFA demonstrates potential in reducing pain levels and improving patient-reported outcomes in individuals with chronic hip pain. Better outcomes were notably associated with the absence of pre-procedure opioid use and higher BMI. Further research is needed to refine patient selection guidelines and to evaluate functional improvements following the procedure.
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