Liam Z Yapp,Chloe E H Scott,Leo Baxendale-Smith,Richard Burnett,Nick D Clement
{"title":"使用全骨水泥单桡骨髁约束假体翻修全膝关节置换术具有良好的10年生存率和改善的结果:一项358个假体的队列研究。","authors":"Liam Z Yapp,Chloe E H Scott,Leo Baxendale-Smith,Richard Burnett,Nick D Clement","doi":"10.1302/0301-620x.107b10.bjj-2024-1619.r1","DOIUrl":null,"url":null,"abstract":"Aims\r\nThe aim of this study was to describe the long-term outcomes following revision total knee arthroplasty (RTKA) using a fully cemented condylar constrained knee (CCK) arthroplasty.\r\n\r\nMethods\r\nThis retrospective study included a consecutive series of patients who underwent RTKA using CCK components (Triathlon Total Stabilizer) in a non-designer centre, between 1 January 2008 and 31 December 2019. There were 344 patients, who underwent 358 revision procedures (330 unilateral and 14 staged bilateral). Their median age was 70.5 years (IQR 63 to 77) and 197 (55.0%) were female. The SPECIFIC criteria were used to define the mode of failure. The median follow-up was 9.8 years (IQR 6.7 to 13.4). Patient-reported outcome measures (PROMs) were collected prospectively (preoperatively, at one year, and at final follow-up (mean 9 years (4 to 16)), using the Oxford Knee Score (OKS) and the EuroQol five-dimension three-level questionnaire (EQ-5D-3L).\r\n\r\nResults\r\nThe indications for RTKA were loosening (n = 131, 36.6%), instability (n = 124, 34.6%), or infection (n = 54, 15.1%). At final follow-up, 102 patients (28.5%) had died, and 30 patients (30 RTKAs; 8.4%) had undergone at least one re-revision, which consisted of secondary patellar resurfacing and/or polyethylene exchange in ten patients (33.3%). The overall ten-year survival was 91.7% (95% CI 88.6 to 94.9); however, this differed significantly (p = 0.029) according to the indication for revision: aseptic loosening, 96.0% (95% CI 92.6 to 99.5); infection, 86.6% (95% CI 77.8 to 96.4); and instability, 85.3% (95% CI 77.4 to 93.9). There were significant (p < 0.001) improvements in PROMs at one year (OKS mean change (MC), 12 (95% CI 11 to 14); and EQ-5D-3L MC, 0.214 (95% CI 0.11 to 0.31)), which were sustained at the final follow-up (OKS MC, 9 (95% CI 7 to 11); and EQ-5D-3L MC, 0.172 (95% CI 0.09 to 0.23)). The patients who underwent revision for aseptic loosening had significantly better OKSs compared with those who underwent revision for infection or instability at both one year (p = 0.008) and at the final follow-up (p = 0.024).\r\n\r\nConclusion\r\nRTKA using a cemented CCK arthroplasty had excellent ten-year survival and clinically meaningful improvements in PROMs. However, revision for instability or infection was associated with significantly worse survival and PROMs.","PeriodicalId":516847,"journal":{"name":"The Bone & Joint Journal","volume":"1 1","pages":"1036-1044"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Revision total knee arthroplasty using a fully cemented single-radius condylar constrained prosthesis has excellent ten-year survival and improvements in outcome measures : a cohort study of 358 implants.\",\"authors\":\"Liam Z Yapp,Chloe E H Scott,Leo Baxendale-Smith,Richard Burnett,Nick D Clement\",\"doi\":\"10.1302/0301-620x.107b10.bjj-2024-1619.r1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aims\\r\\nThe aim of this study was to describe the long-term outcomes following revision total knee arthroplasty (RTKA) using a fully cemented condylar constrained knee (CCK) arthroplasty.\\r\\n\\r\\nMethods\\r\\nThis retrospective study included a consecutive series of patients who underwent RTKA using CCK components (Triathlon Total Stabilizer) in a non-designer centre, between 1 January 2008 and 31 December 2019. There were 344 patients, who underwent 358 revision procedures (330 unilateral and 14 staged bilateral). Their median age was 70.5 years (IQR 63 to 77) and 197 (55.0%) were female. The SPECIFIC criteria were used to define the mode of failure. The median follow-up was 9.8 years (IQR 6.7 to 13.4). Patient-reported outcome measures (PROMs) were collected prospectively (preoperatively, at one year, and at final follow-up (mean 9 years (4 to 16)), using the Oxford Knee Score (OKS) and the EuroQol five-dimension three-level questionnaire (EQ-5D-3L).\\r\\n\\r\\nResults\\r\\nThe indications for RTKA were loosening (n = 131, 36.6%), instability (n = 124, 34.6%), or infection (n = 54, 15.1%). At final follow-up, 102 patients (28.5%) had died, and 30 patients (30 RTKAs; 8.4%) had undergone at least one re-revision, which consisted of secondary patellar resurfacing and/or polyethylene exchange in ten patients (33.3%). The overall ten-year survival was 91.7% (95% CI 88.6 to 94.9); however, this differed significantly (p = 0.029) according to the indication for revision: aseptic loosening, 96.0% (95% CI 92.6 to 99.5); infection, 86.6% (95% CI 77.8 to 96.4); and instability, 85.3% (95% CI 77.4 to 93.9). There were significant (p < 0.001) improvements in PROMs at one year (OKS mean change (MC), 12 (95% CI 11 to 14); and EQ-5D-3L MC, 0.214 (95% CI 0.11 to 0.31)), which were sustained at the final follow-up (OKS MC, 9 (95% CI 7 to 11); and EQ-5D-3L MC, 0.172 (95% CI 0.09 to 0.23)). The patients who underwent revision for aseptic loosening had significantly better OKSs compared with those who underwent revision for infection or instability at both one year (p = 0.008) and at the final follow-up (p = 0.024).\\r\\n\\r\\nConclusion\\r\\nRTKA using a cemented CCK arthroplasty had excellent ten-year survival and clinically meaningful improvements in PROMs. However, revision for instability or infection was associated with significantly worse survival and PROMs.\",\"PeriodicalId\":516847,\"journal\":{\"name\":\"The Bone & Joint Journal\",\"volume\":\"1 1\",\"pages\":\"1036-1044\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Bone & Joint Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1302/0301-620x.107b10.bjj-2024-1619.r1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Bone & Joint Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1302/0301-620x.107b10.bjj-2024-1619.r1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的本研究的目的是描述全膝关节置换术(RTKA)使用完全骨水泥髁约束膝关节(CCK)置换术后的长期结果。方法:本回顾性研究纳入了2008年1月1日至2019年12月31日期间在非设计中心使用CCK组件(Triathlon Total Stabilizer)进行RTKA的连续系列患者。共有344例患者接受了358例翻修手术(330例单侧,14例分阶段双侧)。年龄中位数为70.5岁(IQR 63 ~ 77),女性197例(55.0%)。使用SPECIFIC准则来定义失效模式。中位随访时间为9.8年(IQR为6.7 - 13.4)。采用牛津膝关节评分(OKS)和EuroQol五维三级问卷(EQ-5D-3L)前瞻性地收集患者报告的结果测量(PROMs)(术前、1年和最终随访时(平均9年(4至16年))。结果RTKA的适应症为松动(n = 131, 36.6%)、不稳定(n = 124, 34.6%)、感染(n = 54, 15.1%)。在最后的随访中,102例患者(28.5%)死亡,30例患者(30例rtka, 8.4%)至少进行了一次重新翻修,其中包括10例患者(33.3%)的二次髌骨表面置换和/或聚乙烯置换。总体10年生存率为91.7% (95% CI 88.6 ~ 94.9);然而,根据翻修指征,这一差异显著(p = 0.029):无菌性松动,96.0% (95% CI 92.6至99.5);感染,86.6% (95% CI 77.8 ~ 96.4);和不稳定性,85.3% (95% CI 77.4 - 93.9)。一年后PROMs有显著改善(p < 0.001) (OKS平均变化(MC), 12 (95% CI 11 ~ 14);EQ-5D-3L MC, 0.214 (95% CI 0.11至0.31)),在最后随访时持续(OKS MC, 9 (95% CI 7至11);EQ-5D-3L MC为0.172 (95% CI 0.09 ~ 0.23)。在一年时(p = 0.008)和最后随访时(p = 0.024),因无菌性松动进行翻修的患者的OKSs明显优于因感染或不稳定进行翻修的患者。结论采用骨水泥CCK关节置换术的rtka具有良好的10年生存率和临床意义的改善。然而,不稳定或感染的翻修与生存率和prom显著降低相关。
Revision total knee arthroplasty using a fully cemented single-radius condylar constrained prosthesis has excellent ten-year survival and improvements in outcome measures : a cohort study of 358 implants.
Aims
The aim of this study was to describe the long-term outcomes following revision total knee arthroplasty (RTKA) using a fully cemented condylar constrained knee (CCK) arthroplasty.
Methods
This retrospective study included a consecutive series of patients who underwent RTKA using CCK components (Triathlon Total Stabilizer) in a non-designer centre, between 1 January 2008 and 31 December 2019. There were 344 patients, who underwent 358 revision procedures (330 unilateral and 14 staged bilateral). Their median age was 70.5 years (IQR 63 to 77) and 197 (55.0%) were female. The SPECIFIC criteria were used to define the mode of failure. The median follow-up was 9.8 years (IQR 6.7 to 13.4). Patient-reported outcome measures (PROMs) were collected prospectively (preoperatively, at one year, and at final follow-up (mean 9 years (4 to 16)), using the Oxford Knee Score (OKS) and the EuroQol five-dimension three-level questionnaire (EQ-5D-3L).
Results
The indications for RTKA were loosening (n = 131, 36.6%), instability (n = 124, 34.6%), or infection (n = 54, 15.1%). At final follow-up, 102 patients (28.5%) had died, and 30 patients (30 RTKAs; 8.4%) had undergone at least one re-revision, which consisted of secondary patellar resurfacing and/or polyethylene exchange in ten patients (33.3%). The overall ten-year survival was 91.7% (95% CI 88.6 to 94.9); however, this differed significantly (p = 0.029) according to the indication for revision: aseptic loosening, 96.0% (95% CI 92.6 to 99.5); infection, 86.6% (95% CI 77.8 to 96.4); and instability, 85.3% (95% CI 77.4 to 93.9). There were significant (p < 0.001) improvements in PROMs at one year (OKS mean change (MC), 12 (95% CI 11 to 14); and EQ-5D-3L MC, 0.214 (95% CI 0.11 to 0.31)), which were sustained at the final follow-up (OKS MC, 9 (95% CI 7 to 11); and EQ-5D-3L MC, 0.172 (95% CI 0.09 to 0.23)). The patients who underwent revision for aseptic loosening had significantly better OKSs compared with those who underwent revision for infection or instability at both one year (p = 0.008) and at the final follow-up (p = 0.024).
Conclusion
RTKA using a cemented CCK arthroplasty had excellent ten-year survival and clinically meaningful improvements in PROMs. However, revision for instability or infection was associated with significantly worse survival and PROMs.