A Frozen Elephant Trunk Technique to Reduce Circulatory Arrest Time in Hybrid Aortic Arch for Acute Aortic Dissection: Early and Midterm Outcomes in a Multicentric Cohort of 153 Patients.

OBJECTIVE This study compared the results of the conventional Frozen Elephant Trunk (FET) technique with those of a new approach for the treatment of Acute Aortic Dissection (AAD). SUMMARY BACKGROUND DATA Frozen Elephant Trunk has revolutionized the treatment of extensive aortic pathologies. Hypothermic circulatory arrest is a recommendation for its implementation but remains the greatest burden. Our approach for the FET (Simplified Delivery-FET) procedure allows distal suturing in normothermia with a shorter circulatory arrest time. METHODS This was a non-randomized, multicenter, retrospective study of all patients who underwent total arch replacement for AAD using either the normothermia (SD-FET) or conventional FET (control) techniques. The primary endpoints were in-hospital mortality, stroke, and spinal cord injury. RESULTS One hundred and fifty-three patients were included (n=90 SD-FET; n=63 control FET). Overall, in-hospital mortality was 13.3% (n=20), 10.3% (n=9) in the SD-FET group and 27.5% (n=11) in the control FET group (P=0.206). There were no differences in the rates of postoperative stroke and spinal cord injury. SD-FET was protective for combined outcome (death and/or neurological event) with a corresponding population-average percentage of events of 17.8% (5.3-27.7) in the SD-FET group versus 30.7% (16.5-52.8) in the FET group. The Kaplan-Meier showed a survival rate at 12 and 24 months of 87% in the SD-FET group versus 83% in the FET group and 86% in the SD-FET group versus 80% FET (P=0.625), respectively. CONCLUSIONS The SD-FET technique allows hybrid arch surgery to be performed without cooling and is associated with a lower incidence of the combined criteria of death and/or neurological events.