与其他慢性肝病相比,无创预测代谢功能障碍相关脂肪变性肝病的临床显著门脉高压

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
Muaaz Masood, Ragesh Babu Thandassery
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引用次数: 0

摘要

在目前的临床肝病实践中,肝脏活检很少用于代偿性晚期慢性肝病(cACLD)的诊断。cACLD早期无门静脉高压症,晚期有门静脉高压症。肝静脉压梯度测量是诊断门静脉高压症的金标准,但由于其侵入性,很少使用。最近的Baveno VII共识推荐无创诊断cACLD和临床显著门脉高压(CSPH)的策略。然而,对于预测代谢功能障碍相关脂肪变性肝病(MASLD)患者CSPH的Baveno VII标准的诊断准确性存在一些不确定性。这是相关的,因为MASLD已成为美国cACLD的最重要原因。这篇小型综述概述了Baveno VII标准和其他非侵入性标准在预测由MASLD引起的cACLD患者CSPH时的诊断性能,并与非MASLD原因进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Noninvasive prediction of clinically significant portal hypertension in metabolic dysfunction-associated steatotic liver disease compared to other chronic liver diseases.

Liver biopsy is rarely performed for the diagnosis of compensated advanced chronic liver disease (cACLD) in the current clinical hepatology practice. In the early stage, cACLD presents without portal hypertension, and in the later stage, it presents with portal hypertension. Hepatic venous pressure gradient measurement is the gold standard for diagnosing portal hypertension, but it is rarely used due to its invasive nature. The recent Baveno VII consensus recommends a noninvasive strategy for the diagnosis of cACLD and clinically significant portal hypertension (CSPH). However, there is some uncertainty regarding the diagnostic accuracy of Baveno VII criteria for predicting CSPH among patients with metabolic dysfunction-associated steatotic liver disease (MASLD). This is pertinent as MASLD has become the most important cause of cACLD in the United States. This mini-review outlines the diagnostic performance of Baveno VII criteria and other noninvasive criteria for predicting CSPH in patients with cACLD from MASLD compared to non-MASLD causes.

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来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
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