[1例脊髓及球肌萎缩伴急性双侧声带感染后突然出现麻痹]。

Q4 Medicine
Kazuma Shibata, Akihito Koseki, Youji Suzuki, Naoki Morishita, Nobuhiro Yoshimi, Naoki Sakai
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引用次数: 0

摘要

一名50岁日本男性,感冒症状持续了11天,从就诊当天上午开始就抱怨声音嘶哑、呼吸困难。喉镜检查发现双侧声带麻痹,行气管切开术。具体的入院后访谈显示,他从30岁开始患有姿势性手指震颤,47岁开始出现面部肌肉束状肌痉挛,49岁开始出现轻度吞咽困难。血液检查显示血清CK水平高,胸部计算机断层扫描(CT)显示男性乳房发育,针刺肌电图显示神经源性改变。发现雄激素受体基因CAG重复序列异常扩增(47),诊断为脊髓和球性肌萎缩症(SBMA)。虽然SBMA是声带麻痹的罕见病因,但对于有SBMA病史或体征特征的患者,应将其视为鉴别诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A case of spinal and bulbar muscular atrophy with acute bilateral vocal cord paralysis suddenly apparent after infection].

A 50-year-old Japanese man, who experienced cold symptoms for 11 days, presented to our hospital complaining of hoarseness and dyspnea from the morning of the day of the visit. Laryngoscopy revealed bilateral vocal cord paralysis, and tracheotomy was performed. Specific post-admission interviews revealed that he had suffered from postural finger tremor from 30 years of age, fasciculations of his facial muscle from 47 years of age, and mild dysphagia from 49 years of age. Blood tests showed high serum CK levels, chest computed tomography (CT) revealed gynecomastia, and needle electromyography showed neurogenic changes. An abnormal expansion of the CAG repeat in the androgen receptor gene (47) was found, and spinal and bulbar muscular atrophy (SBMA) was diagnosed. Although SBMA is a rare cause of vocal cord paralysis, this disease should be considered as a differential diagnosis in patients with history or physical findings that are characteristic of SBMA.

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来源期刊
Clinical Neurology
Clinical Neurology Medicine-Neurology (clinical)
CiteScore
0.30
自引率
0.00%
发文量
147
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