沉默自动青霉素交叉反应警报对围手术期抗生素处方和手术部位感染率的影响。

IF 2.9 4区医学 Q2 INFECTIOUS DISEASES

Infection Control and Hospital Epidemiology Pub Date : 2025-09-29 DOI:10.1017/ice.2025.10311

Michael J Durkin, Joshua Nordman, Alice Bewley, Andrew Atkinson, Jonas Marschall, Helen Newland, Kimberly G Blumenthal

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引用次数: 0

摘要

我们使用中断时间序列分析评估了6家医院沉默青霉素交叉反应性警报对围手术期抗生素处方和手术部位感染（ssi）的影响。在青霉素过敏标记的患者中，沉默警报最低限度地增加了头孢唑林的处方（仅敏感性分析；P = 0.03），对ssi没有影响（P = 0.32）。

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Impact of silencing automated penicillin cross-reactivity alerts on perioperative antibiotic prescribing and surgical site infection rates.

We evaluated the impact of silencing penicillin cross-reactivity alerts on perioperative antibiotic prescribing and surgical site infections (SSIs) in 6 hospitals using an interrupted time series analysis. Silencing the alerts minimally increased cefazolin prescribing among penicillin allergy labeled patients (sensitivity analysis only; P = 0.03) and had no influence on SSIs (P = 0.32).

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来源期刊

Infection Control and Hospital Epidemiology 医学-传染病学

CiteScore

6.40

自引率

6.70%

发文量

289

审稿时长

3-8 weeks

期刊介绍： Infection Control and Hospital Epidemiology provides original, peer-reviewed scientific articles for anyone involved with an infection control or epidemiology program in a hospital or healthcare facility. Written by infection control practitioners and epidemiologists and guided by an editorial board composed of the nation''s leaders in the field, ICHE provides a critical forum for this vital information.