学龄儿童和青少年的脂质特征、肥胖指标和心脏代谢危险因素:性别特异性关联

IF 2.9 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Rafał Baran, Joanna Baran, Justyna Leszczak, Anna Bartosiewicz, Justyna Wyszyńska
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引用次数: 0

摘要

背景:儿童肥胖和心脏代谢紊乱是日益增长的全球健康问题。本研究旨在评估学龄儿童和青少年中超重、体脂和特定心脏代谢危险因素的患病率,重点关注性别和年龄相关的差异。方法:对318名6-17岁的波兰参与者进行横断面研究,其中包括169名儿童(6-12岁)和149名青少年(13-17岁)。收集人体测量值、血压(BP)、空腹血脂和血糖测量值,并按年龄组(6-12岁儿童;13-17岁青少年)和性别进行分析。结果:超重和肥胖患病率分别为18.5%(基于bmi)和26.1%(基于体脂)。腹部肥胖和I-II期高血压分别占24.5%和23.6%。与青少年相比,儿童体内脂肪过多、腹部肥胖、血压升高和脂质异常的发生率更高。在青少年中,女孩更常表现为临界/高总胆固醇、低密度脂蛋白(LDL胆固醇)和临界/低高密度脂蛋白(HDL胆固醇),而男孩更常出现血压升高。在女孩中,甘油三酯(TGs)升高与腹部肥胖(优势比(OR) = 2.36, p = 0.015)和高血压(OR = 2.47, p = 0.023)独立相关;在男孩中没有观察到这种联系。结论:心脏代谢危险因素可能在生命早期出现,并因年龄和性别而异。常规筛查和早期干预,特别是针对女孩的脂质异常,对于预防长期健康后果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Lipid Profile, Obesity Indicators and Cardiometabolic Risk Factors in School-Aged Children and Adolescents: Sex-Specific Associations.

Lipid Profile, Obesity Indicators and Cardiometabolic Risk Factors in School-Aged Children and Adolescents: Sex-Specific Associations.

Background: Childhood obesity and cardiometabolic disturbances are growing global health concerns. This study aimed to assess the prevalence of excess body weight, body fat, and selected cardiometabolic risk factors in school-aged children and adolescents, focusing on sex- and age-related differences. Methods: A cross-sectional study was conducted among 318 Polish participants aged 6-17 years, including 169 children (6-12 years) and 149 adolescents (13-17 years). Anthropometric, blood pressure (BP), and fasting blood lipid and glucose measurements were collected and analyzed by age group (children 6-12 years; adolescents 13-17 years) and sex. Results: The prevalence of overweight and obesity was 18.5% (BMI-based) and 26.1% (body fat-based). Abdominal obesity and stage I-II hypertension were observed in 24.5% and 23.6% of participants, respectively. Children had higher rates of excess body fat, abdominal obesity, elevated BP, and lipid abnormalities than adolescents. Among adolescents, girls more frequently presented with borderline/high total cholesterol and Low-Density Lipoprotein (LDL cholesterol) and borderline/low High-Density Lipoprotein (HDL cholesterol), while boys more often had elevated BP. In girls, elevated triglycerides (TGs) were independently associated with abdominal obesity (odds ratio (OR) = 2.36, p = 0.015) and hypertension (OR = 2.47, p = 0.023); no such associations were observed in boys. Conclusions: Cardiometabolic risk factors may appear early in life and differ by age and sex. Routine screening and early interventions, particularly targeting lipid abnormalities in girls, are essential to prevent long-term health consequences.

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来源期刊
Journal of Clinical Medicine
Journal of Clinical Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
5.70
自引率
7.70%
发文量
6468
审稿时长
16.32 days
期刊介绍: Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals. Unique features of this journal: manuscripts regarding original research and ideas will be particularly welcomed.JCM also accepts reviews, communications, and short notes. There is no limit to publication length: our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.
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