哪里有贫困——主动和被动寻找病例,以解决莫桑比克对坏疽性口炎的忽视问题。

IF 6.1 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Marta Ribes, Abdala Atumane, Fernando Padama, Filipe Abrigio, Milagre Andurage, Yosney Arbolaez, Eldo Elobolobo, Claire Jeantet, Gemma Moncunill, Tairo Sumine, Luis Transval, Marta Mapengo, Carlos Chaccour
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引用次数: 0

摘要

简介:坏疽性口炎是一种进展迅速,毁容的口腔面部坏死性感染,主要影响生活在贫困中的儿童。迄今为止,没有报告莫桑比克坏疽性口炎的原始数据。我们的目的是首次收集关于莫桑比克赞比西亚省持续存在的坏疽性口炎的经验证据。方法:我们在参考医院的颌面和儿科病房采用被动病例搜索方法来识别急性坏疽性口炎病例。为了寻找坏疽性口炎幸存者,我们开展了以社区为基础的主动病例搜索,向潜在的举报者人群展示坏疽性口炎后遗症的海报。我们访问了该省22个区中的12个,并对每个确诊的坏疽性口炎病例进行了问卷调查。结果:在5周的时间内,确定了2例急性坏疽性口炎病例和21例1971 - 2015年间患过坏疽性口炎的幸存者。采用18.75%的队列估计就诊比例,并假设存活率为10%,则赞比西亚农村地区的年发病率估计为每10万名9岁以下儿童13.7例,这表明该地区每年至少发生213例坏疽性口炎病例。结论:数据的完全缺乏并不意味着在莫桑比克不存在坏疽性口炎。这项研究提供了一种简单的方法来快速识别高风险地区和人群中的坏疽性口炎病例。哪里有贫困,哪里就可能有坏疽性口炎。全世界迫切需要提高认识、报告和公共卫生干预措施,以制止这种可预防和可治疗疾病的后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Wherever there is poverty - active and passive case finding to address neglect of noma in Mozambique.

Introduction: Noma is a rapidly progressing, disfiguring orofacial necrotising infection that primarily affects children living in poverty. To date, there are no primary data reporting noma in Mozambique. Our aim was to collect empirical evidence on the ongoing presence of noma in Zambezia Province, Mozambique, for the first time.

Methods: We used a passive case search approach at the maxillofacial and paediatric wards of the reference hospital to identify acute noma cases. To find noma survivors, we conducted a community-based active case search, showing posters of noma sequelae to crowds of potential informants. We visited 12 of the 22 districts in the province and administered a questionnaire to each confirmed noma case.

Results: Over a 5-week period, two acute noma cases and 21 survivors having had noma between 1971 and 2015 were identified. Using a cohort-estimated healthcare-seeking proportion of 18.75% and assuming a survival rate of 10%, the annual incidence in rural areas of Zambezia was estimated at 13.7 per 100 000 children under the age of nine years, suggesting that at least 213 noma cases occur yearly in the region.

Conclusion: The total lack of data does not mean noma is non-existent in Mozambique. This study provides a simple methodology to rapidly identify noma cases in high-risk areas and populations. Noma is likely present wherever there is poverty. Increased awareness, reporting and public health interventions are urgently needed worldwide to stop the consequences of this preventable and treatable disease.

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来源期刊
BMJ Global Health
BMJ Global Health Medicine-Health Policy
CiteScore
11.40
自引率
4.90%
发文量
429
审稿时长
18 weeks
期刊介绍: BMJ Global Health is an online Open Access journal from BMJ that focuses on publishing high-quality peer-reviewed content pertinent to individuals engaged in global health, including policy makers, funders, researchers, clinicians, and frontline healthcare workers. The journal encompasses all facets of global health, with a special emphasis on submissions addressing underfunded areas such as non-communicable diseases (NCDs). It welcomes research across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialized studies. The journal also encourages opinionated discussions on controversial topics.
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