Cross-Coupling Reactions of Organometallic Derivatives of Nitronyl Nitroxides with Aryl Halides Catalyzed by Palladium Complexes (A Review)

Sterically hindered 2-imidazoline-3-oxide-1-oxyls (nitronyl nitroxides) are a class of organic radicals that are widely used in the field of molecular design of magnets and spintronic devices. Over the past decade, the most significant advances in the chemistry and function-oriented synthesis of nitronyl nitroxide radicals have been achieved through palladium-catalyzed cross-coupling reaction of organometallic derivatives of nitronyl nitroxides with aryl halides. The review presents the development of this field, the challenges encountered in the application of the cross-coupling reaction in the chemistry of nitronyl nitroxides, and the solutions found that made it possible to implement the targeted synthesis of organic high-spin systems.