含核糖和脱氧核糖多核苷酸的亚甲基蓝配合物的荧光性质研究

IF 0.4 4区物理与天体物理 Q4 PHYSICS, MULTIDISCIPLINARY

Journal of Contemporary Physics (Armenian Academy of Sciences) Pub Date : 2025-07-04 DOI:10.1134/S1068337225700264

A. P. Antonyan, M. A. Parsadanyan, A. H. Karapetyan, P. O. Vardevanyan

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引用次数: 0

摘要

研究了ss-poly（dA）、poly（rU）、poly（rA）、poly（dT）以及ds-杂化结构poly(rA)-poly（dT）和poly(dA)-poly（rU）的MB配合物的荧光特性。根据荧光光谱和吸收光谱的变化，发现该配体对同多核苷酸序列具有不相等的亲和力。特别是，与ss-poly(dA), poly（rU）和poly（dT）相比，MS与poly（rA）结合具有明显的特异性。MB与杂化ds-多核苷酸poly(rA)-poly（dT）和poly(dA)-poly（rU）的相互作用也存在差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Study of Fluorescent Properties of Methylene Blue Complexes with Ribo- and Deoxyribo-Polynucleotides

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Study of Fluorescent Properties of Methylene Blue Complexes with Ribo- and Deoxyribo-Polynucleotides

A study of the fluorescent properties of MB complexes with ss-poly(dA), poly(rU), poly(rA), and poly(dT), as well as hybrid ds-structures poly(rA)-poly(dT) and poly(dA)-poly(rU), was carried out. Based on changes in fluorescence and absorption spectra, it was revealed that this ligand exhibits unequal affinity for homopolynucleotide sequences. Particularly, it was found that MS binds to poly(rA) with pronounced specificity, compared to ss-poly(dA), poly(rU), and poly(dT). The difference was also obtained for the interaction of MB with hybrid ds-polynucleotides poly(rA)-poly(dT) and poly(dA)-poly(rU).

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来源期刊

Journal of Contemporary Physics (Armenian Academy of Sciences) PHYSICS, MULTIDISCIPLINARY-

CiteScore

1.00

自引率

66.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Contemporary Physics (Armenian Academy of Sciences) is a journal that covers all fields of modern physics. It publishes significant contributions in such areas of theoretical and applied science as interaction of elementary particles at superhigh energies, elementary particle physics, charged particle interactions with matter, physics of semiconductors and semiconductor devices, physics of condensed matter, radiophysics and radioelectronics, optics and quantum electronics, quantum size effects, nanophysics, sensorics, and superconductivity.