一例青少年股骨远端骨肉瘤:用冷冻手术-再生骨,半膝关节置换术和orif挽救肢体的病例报告

IF 0.7 Q4 SURGERY
Bangkit Primayudha, Muhamad Naseh Sajadi Budi, Wilson Wijaya, Mohammad Syarif Mas'ud
{"title":"一例青少年股骨远端骨肉瘤:用冷冻手术-再生骨,半膝关节置换术和orif挽救肢体的病例报告","authors":"Bangkit Primayudha,&nbsp;Muhamad Naseh Sajadi Budi,&nbsp;Wilson Wijaya,&nbsp;Mohammad Syarif Mas'ud","doi":"10.1016/j.ijscr.2025.111957","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>This report presents a rare case of distal femoral osteosarcoma in an 11-year-old boy, managed through a hybrid limb-salvage approach combining cryosurgery-recycled bone, hemi knee arthroplasty, and internal fixation. The objective is to detail the surgical technique and assess short-term functional outcomes, particularly in adolescents with juxta-articular osteosarcoma.</div></div><div><h3>Presentation of case</h3><div>The patient presented with a three-month history of progressive right knee pain and swelling. Radiographs indicated classic osteosarcoma features, including a sunburst pattern and Codman's triangle. In the absence of biopsy and advanced imaging, diagnosis was made clinically and radiologically. Following 2 cycles of neoadjuvant chemotherapy, wide resection of the tumor was performed. The excised bone was treated with liquid nitrogen cryoablation and reimplanted as a recycled autograft. Knee joint reconstruction was completed using a cemented polyethylene hemiarthroplasty on the tibial side, with the femoral segment stabilized using a lateral locking plate. Postoperative recovery was smooth, with the patient achieving excellent functional outcomes within six months. No recurrence or metastasis was noted during follow-up.</div></div><div><h3>Discussion</h3><div>This case demonstrates the clinical feasibility of combining cryo-treated autograft and hemiarthroplasty for biologic limb reconstruction in pediatric patients. The technique preserves native anatomy, reduces donor site complications, and provides a cost-effective alternative to megaprostheses—making it particularly suitable for low-resource settings.</div></div><div><h3>Conclusion</h3><div>Cryosurgery-recycled autograft combined with hemi knee replacement and internal fixation is a promising limb-salvage strategy offering favorable oncological and functional outcomes in managing pediatric osteosarcoma.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"136 ","pages":"Article 111957"},"PeriodicalIF":0.7000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Distal femur osteosarcoma in an adolescent: Limb salvage with cryosurgery-recycled bone, hemi knee replacement, and ORIF—A case report\",\"authors\":\"Bangkit Primayudha,&nbsp;Muhamad Naseh Sajadi Budi,&nbsp;Wilson Wijaya,&nbsp;Mohammad Syarif Mas'ud\",\"doi\":\"10.1016/j.ijscr.2025.111957\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>This report presents a rare case of distal femoral osteosarcoma in an 11-year-old boy, managed through a hybrid limb-salvage approach combining cryosurgery-recycled bone, hemi knee arthroplasty, and internal fixation. The objective is to detail the surgical technique and assess short-term functional outcomes, particularly in adolescents with juxta-articular osteosarcoma.</div></div><div><h3>Presentation of case</h3><div>The patient presented with a three-month history of progressive right knee pain and swelling. Radiographs indicated classic osteosarcoma features, including a sunburst pattern and Codman's triangle. In the absence of biopsy and advanced imaging, diagnosis was made clinically and radiologically. Following 2 cycles of neoadjuvant chemotherapy, wide resection of the tumor was performed. The excised bone was treated with liquid nitrogen cryoablation and reimplanted as a recycled autograft. Knee joint reconstruction was completed using a cemented polyethylene hemiarthroplasty on the tibial side, with the femoral segment stabilized using a lateral locking plate. Postoperative recovery was smooth, with the patient achieving excellent functional outcomes within six months. No recurrence or metastasis was noted during follow-up.</div></div><div><h3>Discussion</h3><div>This case demonstrates the clinical feasibility of combining cryo-treated autograft and hemiarthroplasty for biologic limb reconstruction in pediatric patients. The technique preserves native anatomy, reduces donor site complications, and provides a cost-effective alternative to megaprostheses—making it particularly suitable for low-resource settings.</div></div><div><h3>Conclusion</h3><div>Cryosurgery-recycled autograft combined with hemi knee replacement and internal fixation is a promising limb-salvage strategy offering favorable oncological and functional outcomes in managing pediatric osteosarcoma.</div></div>\",\"PeriodicalId\":48113,\"journal\":{\"name\":\"International Journal of Surgery Case Reports\",\"volume\":\"136 \",\"pages\":\"Article 111957\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Surgery Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210261225011435\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Surgery Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210261225011435","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0

摘要

本报告报告了一例罕见的11岁男孩股骨远端骨肉瘤,通过冷冻手术-再生骨,半膝关节置换术和内固定相结合的混合保肢入路治疗。目的是详细的手术技术和评估短期功能结果,特别是在青少年关节旁骨肉瘤。患者有三个月的进行性右膝疼痛和肿胀史。x线片显示典型的骨肉瘤特征,包括太阳斑和Codman三角形。在没有活检和高级影像学检查的情况下,通过临床和放射学进行诊断。经过2个周期的新辅助化疗后,行肿瘤大范围切除。切除的骨用液氮冷冻消融处理,并作为再生自体移植物重新植入。胫骨侧采用骨水泥聚乙烯半关节置换术完成膝关节重建,股骨段采用外侧锁定钢板稳定。术后恢复顺利,患者在6个月内获得了良好的功能预后。随访期间未见复发或转移。本病例证明冷冻自体移植物与半关节置换术联合用于小儿生物肢体重建的临床可行性。该技术保留了原始解剖结构,减少了供体部位并发症,并为大型假体提供了一种经济有效的替代方案,使其特别适合资源匮乏的环境。结论冷冻手术-再生自体移植物联合半膝关节置换术和内固定是治疗小儿骨肉瘤的一种有前景的保肢策略,具有良好的肿瘤和功能效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Distal femur osteosarcoma in an adolescent: Limb salvage with cryosurgery-recycled bone, hemi knee replacement, and ORIF—A case report

Introduction

This report presents a rare case of distal femoral osteosarcoma in an 11-year-old boy, managed through a hybrid limb-salvage approach combining cryosurgery-recycled bone, hemi knee arthroplasty, and internal fixation. The objective is to detail the surgical technique and assess short-term functional outcomes, particularly in adolescents with juxta-articular osteosarcoma.

Presentation of case

The patient presented with a three-month history of progressive right knee pain and swelling. Radiographs indicated classic osteosarcoma features, including a sunburst pattern and Codman's triangle. In the absence of biopsy and advanced imaging, diagnosis was made clinically and radiologically. Following 2 cycles of neoadjuvant chemotherapy, wide resection of the tumor was performed. The excised bone was treated with liquid nitrogen cryoablation and reimplanted as a recycled autograft. Knee joint reconstruction was completed using a cemented polyethylene hemiarthroplasty on the tibial side, with the femoral segment stabilized using a lateral locking plate. Postoperative recovery was smooth, with the patient achieving excellent functional outcomes within six months. No recurrence or metastasis was noted during follow-up.

Discussion

This case demonstrates the clinical feasibility of combining cryo-treated autograft and hemiarthroplasty for biologic limb reconstruction in pediatric patients. The technique preserves native anatomy, reduces donor site complications, and provides a cost-effective alternative to megaprostheses—making it particularly suitable for low-resource settings.

Conclusion

Cryosurgery-recycled autograft combined with hemi knee replacement and internal fixation is a promising limb-salvage strategy offering favorable oncological and functional outcomes in managing pediatric osteosarcoma.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.10
自引率
0.00%
发文量
1116
审稿时长
46 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信