神经源性吞咽困难:周围和中枢神经调节。

IF 2.2 Q2 MEDICINE, GENERAL & INTERNAL
Mario Stampanoni Bassi, Diego Centonze, Bledar Gjikolaj, Angelo Alito, Adriana Tisano, Rosario Marchese-Ragona, Domenico Antonio Restivo
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引用次数: 0

摘要

吞咽困难是神经系统疾病患者中一种常见且可能危及生命的并发症。吞咽是一种复杂的神经生理机制,受广泛的中枢神经系统区域网络的调控。吞咽功能的控制需要位于脑干、感觉运动皮层、基底神经节和小脑的中央模式发生器的完整性,也需要周围神经和吞咽肌肉的完整性。影响该系统中枢或外周部分的神经系统疾病通常会导致吞咽困难。尽管其临床相关性,神经源性吞咽困难的管理仍然具有挑战性。虽然吞咽治疗等康复策略目前是主要的治疗选择,但新出现的证据表明,非侵入性中枢和周围神经调节技术可能提供辅助的有益效果。有必要进一步研究以更好地确定其疗效、最佳方案和长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurogenic Dysphagia: Peripheral and Central Neuromodulation.

Dysphagia is a frequent and potentially life-threatening complication in patients with neurological disorders. Swallowing is a complex neurophysiological mechanism regulated by a widespread network of central nervous system regions. The control of swallowing functions requires the integrity of the central pattern generator located in the brainstem, the sensorimotor cortex, the basal ganglia, and the cerebellum, but also peripheral nerves and swallowing muscles. Neurological diseases affecting either central or peripheral components of this system commonly result in dysphagia. Despite its clinical relevance, the management of neurogenic dysphagia remains challenging. While rehabilitative strategies such as swallowing therapy currently represent the main treatment option, emerging evidence suggests that non-invasive central and peripheral neuromodulation techniques may provide adjunctive beneficial effects. Further research is warranted to better define their efficacy, optimal protocols, and long-term outcomes.

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来源期刊
Clinics and Practice
Clinics and Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
4.30%
发文量
91
审稿时长
10 weeks
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