甲状腺功能减退对腕管综合征发病风险及电诊断参数的影响。

IF 3 Q2 CLINICAL NEUROLOGY
Ahmad R Abuzinadah
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引用次数: 0

摘要

背景:甲状腺功能减退已被认为是腕管综合征(CTS)的危险因素。然而,甲状腺功能减退对CTS风险的影响尚未在大型非选择性临床人群中进行研究,甲状腺功能减退对电诊断参数的影响仍未充分了解。方法:在这项回顾性研究中,我们检查了480例上肢电诊断评估患者。我们比较了有和没有甲状腺功能减退的患者中CTS的患病率,调整了年龄和性别。此外,我们比较了正中神经感觉和运动潜伏期和比较潜伏期研究(COLS)[通过掌差(Palmdiff)和环差研究(Ringdiff)进行中尺比较;并通过拇指差异研究(Thumbdiff)]对有和无甲状腺功能减退症患者进行中位至径向比较,按CTS状态和年龄组分层。结果:甲减患者CTS粗患病率(79.7%)高于无甲减患者(61.8%)(p = 0.005)。然而,在调整了年龄和性别后,logistic回归分析显示甲状腺功能减退与CTS之间的相关性不显著(校正优势比(OR): 1.71;95% CI: 0.89-3.28, p = 0.106)。CTS在50岁以下甲状腺功能减退患者中更为普遍(OR: 2.59; 95% CI: 1.17-5.73, p = 0.018)。在CTS组和非CTS组中,有和没有甲状腺功能减退的患者在任何电诊断参数上没有显著差异。结论:甲状腺功能减退增加了50岁以下患者发生CTS的风险。用于CTS诊断的电诊断参数不受甲状腺功能减退的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Hypothyroidism on the Risk of Carpal Tunnel Syndrome and Electrodiagnostic Parameters.

Background: Hypothyroidism has been implicated as a risk factor for carpal tunnel syndrome (CTS). However, the effect of hypothyroidism on the risk of CTS has not been studied in large, non-selective clinic populations, and the impact of hypothyroidism on electrodiagnostic parameters remains inadequately understood.

Methods: In this retrospective study, we examined 480 patients referred for upper limb electrodiagnostic evaluation. We compared the prevalence of CTS among patients with and without hypothyroidism, adjusting for age and gender. Additionally, we compared the median nerve sensory and motor latencies and comparative latency studies (COLS) [median-to-ulnar comparison through palmar difference (Palmdiff) and ring difference studies (Ringdiff); and median-to-radial comparison through a thumb difference study (Thumbdiff)] among patients with and without hypothyroidism disease, stratified by CTS status and age groups.

Results: The crude prevalence of CTS was higher among patients with hypothyroidism (79.7%) compared to those without (61.8%) (p = 0.005). However, after adjusting for age and gender, logistic regression analysis revealed a non-significant association between hypothyroidism and CTS (adjusted odds ratio (OR): 1.71; 95% CI: 0.89-3.28, p = 0.106). CTS was more prevalent among patients with hypothyroidism under 50 years of age (OR: 2.59; 95% CI: 1.17-5.73, p = 0.018). There were no significant differences in any electrodiagnostic parameters between patients with and without hypothyroidism among CTS and non-CTS groups.

Conclusions: Hypothyroidism increased the risk of CTS among patients under 50 years of age. The electrodiagnostic parameters used for CTS diagnosis were not influenced by the presence of hypothyroidism.

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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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