高龄腕管综合征:187例患者的临床、电诊断和超声特征

IF 3 Q2 CLINICAL NEUROLOGY
Lisa B E Shields, Vasudeva G Iyer, Theresa Kluthe, Yi Ping Zhang, Christopher B Shields
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引用次数: 0

摘要

背景/目的:与年轻患者相比,老年腕管综合征(CTS)患者有更严重的临床、超声和电诊断(EDX)表现。在老年CTS患者中,足底无力和萎缩在首发时更为常见。方法:回顾性分析187例高龄(80岁及以上)EDX确诊为CTS的患者。我们描述了这些患者的临床、EDX和US特征,并比较了中年队列(40-50岁)的EDX结果对腕管正中神经卡压(CT)的严重程度。结果:特高龄手CTS共289例(187例,双侧症状102例)。289只手中,75只手(26.0%)出现鱼际萎缩,178只手(61.6%)出现拇短外展肌无力,265只手(91.7%)出现针刺减少或消失。289只手中,57只手(66.3%)的正中神经刺激未引起APB和第二蚓状肌的复合肌肉动作电位。211例(76.2%)手部未检测到感觉神经动作电位。比较各种超声测量对CTS诊断的灵敏度,CT进口截面积在各种测量中灵敏度最高。随着CT进气道CSA的增加,EDX研究中CTS严重程度增加的几率也增加(OR = 1.109, p值= 0.001)。与中年CTS患者相比,老年CTS患者发生严重CTS的频率更高(χ 2 = 102.653, p值< 0.001)。结论:老年患者似乎只有在CTS变得严重时才寻求医疗护理。初级保健医生应该在老年人中寻找CTS的体征和症状,并鼓励及时治疗。外科医生应该认识到临床、EDX和美国研究在老年CTS患者队列中的差异。当EDX研究在严重CTS中变得不定位时,US在评估CTS时非常有用,这常见于老年患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carpal Tunnel Syndrome in the Very Elderly: Clinical, Electrodiagnostic, and Ultrasound Features in a Cohort of 187 Patients.

Background/objectives: Elderly patients with carpal tunnel syndrome (CTS) have more severe clinical, ultrasonic, and electrodiagnostic (EDX) findings compared to younger patients. Thenar weakness and atrophy are more common at initial presentation in the elderly population with CTS.

Methods: This is a retrospective review of 187 very elderly patients (aged 80 years and older) with EDX confirmation of CTS. We describe the clinical, EDX, and US features in these patients and compare the severity of the median nerve entrapment at the carpal tunnel (CT) by EDX findings to a middle-aged cohort (ages 40-50 years).

Results: The total number of very elderly hands with CTS was 289 (187 patients total, with bilateral symptoms in 102 patients). Of the 289 hands, thenar atrophy was observed in 75 (26.0%) hands, weakness of the abductor pollicis brevis (APB) muscle was detected in 178 (61.6%) hands, and pinprick decrease/loss was noted in 265 (91.7%) hands. Of the total 289 hands, 57 (66.3%) hands' median nerve stimulation did not evoke compound muscle action potentials over the APB and second lumbrical muscles. Sensory nerve action potentials were not detected in 211 (76.2%) hands. Comparing the sensitivities of various US measurements in diagnosing CTS, the cross-sectional area at the CT inlet had the highest sensitivity among the various measurements. As the CSA at the CT inlet increases, the odds of a greater CTS severity by EDX studies also increase (OR = 1.109, p-value = 0.001). The very elderly patients with CTS more frequently had more severe CTS compared to the middle-aged patients with CTS (chi-squared = 102.653, p-value < 0.001).

Conclusions: The very elderly patients appear to seek medical care only when the CTS has become severe. The primary care physicians should look for signs and symptoms of CTS in the very elderly and encourage prompt treatment. Surgeons should be cognizant of the differences in the clinical, EDX, and US studies in the very elderly patient cohort with CTS. US is highly useful in evaluating CTS when the EDX studies become non-localizing in severe CTS, as often seen in the very elderly patients.

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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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