异戊二烯蛋白A四环核的构建。

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-09-25 DOI:10.1021/acs.orglett.5c03589

Ning Liang, , , Xujuan Su, , , Huaxuan Zhang, , , Yue Liu, , , Xingang Xie*, , and , Xuegong She,

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引用次数: 0

摘要

异abietenin A是新分离的具有复杂四环结构的芳香abietane。在此，我们报道了一个通过分子内芳Diels-Alder环加成反应实现的6/6/6/5四环核的简明结构。在环A和环B之间所需的传递模式是通过烯丙基重氮重排反应组装的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Construction of the Tetracyclic Core of Isoabietenin A

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Construction of the Tetracyclic Core of Isoabietenin A

Isoabietenin A is a newly isolated aromatic abietane with a complex tetracyclic framework. Herein, we report a concise construction of its characteristic 6/6/6/5 tetracyclic core enabled by an intramolecular aryne Diels–Alder cycloaddition reaction. The required trans-fused pattern between rings A and B was assembled by an allylic diazene rearrangement reaction.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.