Timiya S Nolan, Amaris Williams, Shannon L Gillespie, Tamar Gur, Daniel Walker, Jennifer A Garner, Jeff Galley, Luiza Reopell, Amani Wilson, Kwame Lartey, Nnanna Ojembe, Aryn Hubbard, Joseph Ballas, Bhavya Appana, Emmanuella Aboagye-Mensah, Shabrya Smith, Madison Griffin, Songzhu Zhao, Guy N Brock, Carrie Baker, Jenelle Hoseus, Diana Briggs, John Gregory, Mysheika W Roberts, Makeda Porter, Joshua J Joseph
{"title":"黑色影响的设计：一项评估心血管健康干预中潜在心理社会压力减少机制的随机对照试验。","authors":"Timiya S Nolan, Amaris Williams, Shannon L Gillespie, Tamar Gur, Daniel Walker, Jennifer A Garner, Jeff Galley, Luiza Reopell, Amani Wilson, Kwame Lartey, Nnanna Ojembe, Aryn Hubbard, Joseph Ballas, Bhavya Appana, Emmanuella Aboagye-Mensah, Shabrya Smith, Madison Griffin, Songzhu Zhao, Guy N Brock, Carrie Baker, Jenelle Hoseus, Diana Briggs, John Gregory, Mysheika W Roberts, Makeda Porter, Joshua J Joseph","doi":"10.1161/JAHA.124.039380","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Lower attainment of cardiovascular health (CVH), indicated by lower scores on the American Heart Association's Life's Essential 8 metrics, is a major contributor to Black men having the shortest life expectancy of any nonindigenous race/sex group. Evidence-based community interventions to improve CVH in Black men are sparse; thus, an academic-community-government-industry partnership was developed to cocreate and test a 24-week CVH intervention for Black men, Black Impact, in line with best practices for community-based participatory research.</p><p><strong>Methods and results: </strong>The Black Impact intervention is delivered by health coaches, fitness trainers, and community health workers and emphasizes weekly physical activity, health education, and addressing social needs. Together, academic-community-government-industry partners will conduct a randomized, waitlist-controlled trial among 340 Black men with suboptimal CVH to determine intervention: (1) efficacy on CVH and psychosocial stress; (2) effect on individual and interpersonal outcomes; (3) effect on biological mechanisms responsive to psychosocial stress; and (4) organizational contexts and resources necessary for sustainability of the academic-community-government-industry partnership. An intervention working group of academic-community-government-industry partner representatives will guide implementation and evaluation. Upon trial completion, findings (eg, change in CVH at 24 weeks [primary], change in perceived stress at 24 weeks [coprimary], biological mechanisms, psychosocial process mediators [stress, social and interpersonal processes]) will be disseminated in scientific and lay settings.</p><p><strong>Conclusions: </strong>Robust clinical trials are needed to test novel interventions focused on CVH equity. Black Impact will determine intervention efficacy, evaluate biological and psychosocial mediators of impact, and lay a framework for sustainability and scalability.</p><p><strong>Registration: </strong>URL: https://clinicaltrials.gov/; Unique Identifier: NCT06055036.</p>","PeriodicalId":54370,"journal":{"name":"Journal of the American Heart Association","volume":" ","pages":"e039380"},"PeriodicalIF":5.3000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Design of Black Impact: A Randomized Controlled Trial Evaluating the Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention.\",\"authors\":\"Timiya S Nolan, Amaris Williams, Shannon L Gillespie, Tamar Gur, Daniel Walker, Jennifer A Garner, Jeff Galley, Luiza Reopell, Amani Wilson, Kwame Lartey, Nnanna Ojembe, Aryn Hubbard, Joseph Ballas, Bhavya Appana, Emmanuella Aboagye-Mensah, Shabrya Smith, Madison Griffin, Songzhu Zhao, Guy N Brock, Carrie Baker, Jenelle Hoseus, Diana Briggs, John Gregory, Mysheika W Roberts, Makeda Porter, Joshua J Joseph\",\"doi\":\"10.1161/JAHA.124.039380\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Lower attainment of cardiovascular health (CVH), indicated by lower scores on the American Heart Association's Life's Essential 8 metrics, is a major contributor to Black men having the shortest life expectancy of any nonindigenous race/sex group. Evidence-based community interventions to improve CVH in Black men are sparse; thus, an academic-community-government-industry partnership was developed to cocreate and test a 24-week CVH intervention for Black men, Black Impact, in line with best practices for community-based participatory research.</p><p><strong>Methods and results: </strong>The Black Impact intervention is delivered by health coaches, fitness trainers, and community health workers and emphasizes weekly physical activity, health education, and addressing social needs. Together, academic-community-government-industry partners will conduct a randomized, waitlist-controlled trial among 340 Black men with suboptimal CVH to determine intervention: (1) efficacy on CVH and psychosocial stress; (2) effect on individual and interpersonal outcomes; (3) effect on biological mechanisms responsive to psychosocial stress; and (4) organizational contexts and resources necessary for sustainability of the academic-community-government-industry partnership. An intervention working group of academic-community-government-industry partner representatives will guide implementation and evaluation. Upon trial completion, findings (eg, change in CVH at 24 weeks [primary], change in perceived stress at 24 weeks [coprimary], biological mechanisms, psychosocial process mediators [stress, social and interpersonal processes]) will be disseminated in scientific and lay settings.</p><p><strong>Conclusions: </strong>Robust clinical trials are needed to test novel interventions focused on CVH equity. 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Design of Black Impact: A Randomized Controlled Trial Evaluating the Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention.
Background: Lower attainment of cardiovascular health (CVH), indicated by lower scores on the American Heart Association's Life's Essential 8 metrics, is a major contributor to Black men having the shortest life expectancy of any nonindigenous race/sex group. Evidence-based community interventions to improve CVH in Black men are sparse; thus, an academic-community-government-industry partnership was developed to cocreate and test a 24-week CVH intervention for Black men, Black Impact, in line with best practices for community-based participatory research.
Methods and results: The Black Impact intervention is delivered by health coaches, fitness trainers, and community health workers and emphasizes weekly physical activity, health education, and addressing social needs. Together, academic-community-government-industry partners will conduct a randomized, waitlist-controlled trial among 340 Black men with suboptimal CVH to determine intervention: (1) efficacy on CVH and psychosocial stress; (2) effect on individual and interpersonal outcomes; (3) effect on biological mechanisms responsive to psychosocial stress; and (4) organizational contexts and resources necessary for sustainability of the academic-community-government-industry partnership. An intervention working group of academic-community-government-industry partner representatives will guide implementation and evaluation. Upon trial completion, findings (eg, change in CVH at 24 weeks [primary], change in perceived stress at 24 weeks [coprimary], biological mechanisms, psychosocial process mediators [stress, social and interpersonal processes]) will be disseminated in scientific and lay settings.
Conclusions: Robust clinical trials are needed to test novel interventions focused on CVH equity. Black Impact will determine intervention efficacy, evaluate biological and psychosocial mediators of impact, and lay a framework for sustainability and scalability.
期刊介绍：
As an Open Access journal, JAHA - Journal of the American Heart Association is rapidly and freely available, accelerating the translation of strong science into effective practice.
JAHA is an authoritative, peer-reviewed Open Access journal focusing on cardiovascular and cerebrovascular disease. JAHA provides a global forum for basic and clinical research and timely reviews on cardiovascular disease and stroke. As an Open Access journal, its content is free on publication to read, download, and share, accelerating the translation of strong science into effective practice.
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