急诊快速通道对急性脑卒中治疗时间和结局的影响:系统回顾和荟萃分析。

IF 2.3 3区 医学 Q1 EMERGENCY MEDICINE
Ying Shen, Yuying Lao, Xiening Xu
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引用次数: 0

摘要

目的:系统评价急诊快速通道在提高急性脑卒中管理效率和临床效果方面的效果,为优化急诊护理流程提供循证支持。方法:综合检索中国知网、万方数据、VIP数据库、PubMed、Embase、Web of Science、Cochrane图书馆等文献,筛选急诊快速通道在急性脑卒中中的应用研究。使用Review Manager 5.4软件进行数据综合。主要指标包括院前候诊时间、入院至诊断时间、诊断至治疗时间、急诊快速通道停留时间、抢救成功率和患者满意度。敏感性分析用于评估结果的稳健性,发表偏倚采用Begg's和Egger's检验进行评估。结果:共纳入30项研究。荟萃分析表明,紧急快速通道显著降低院前等待时间(MD = - 4.65, 95%置信区间CI: 5.76 - 3.53),从住院到诊断(MD = - 8.13, 95%置信区间CI: 9.32 - 6.93),从诊断到治疗(MD = - 10.95, 95%置信区间CI: 12.32 - 9.59),和紧急快速通道持续时间(MD = - 7.47, 95%置信区间CI: 9.30 - 5.64),同时显著提高救助成功率(或= 5.71,95% CI: 4.48—7.27)。大多数结果没有明显的发表偏倚,敏感性分析证实了结果的稳定性。结论:紧急快速通道方案显著缩短了急性/重症监护路径的关键时间框架,包括:院前延迟、进门到成像时间、成像到治疗间隔和快速通道停留时间。同时提高了抢救成功率(成功稳定患者比例)。这些已证实的临床益处支持其在卒中急救系统中的广泛实施。建议通过多中心高质量试验进一步验证,以确定疗效的普遍性。临床试验号:不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of emergency fast track on treatment time and outcomes in acute stroke: a systematic review and meta-analysis.

Objective: To systematically evaluate the effectiveness of emergency fast track in improving the efficiency of acute stroke management and enhancing clinical outcomes, thereby providing evidence-based support for optimizing emergency care workflows.

Methods: A comprehensive literature search was conducted in CNKI, Wanfang Data, VIP Database, PubMed, Embase, Web of Science, and the Cochrane Library to identify studies on the application of emergency fast track in acute stroke. Data synthesis was performed using Review Manager 5.4 software. The primary measures included pre-hospital waiting time, time from hospital admission to diagnosis, time from diagnosis to treatment, length of stay in the emergency fast track, rescue success rate, and patient satisfaction rate. Sensitivity analysis was used to assess the robustness of the results, and publication bias was evaluated using Begg's and Egger's tests.

Results: A total of 30 studies were included. The meta-analysis indicated that emergency fast track significantly reduced pre-hospital waiting time (MD = - 4.65, 95% CI: - 5.76 to - 3.53), time from hospital admission to diagnosis (MD = - 8.13, 95% CI: - 9.32 to - 6.93), time from diagnosis to treatment (MD = - 10.95, 95% CI: - 12.32 to - 9.59), and emergency fast track duration (MD = - 7.47, 95% CI: - 9.30 to - 5.64), while significantly increasing the rescue success rate (OR = 5.71, 95% CI: 4.48 to 7.27). Most outcomes showed no significant publication bias, and sensitivity analyses confirmed the stability of the results.

Conclusion: The emergency fast-track protocol significantly reduces critical timeframes in acute/critical care pathways, including: pre-hospital delay, door-to-imaging time, imaging-to-treatment interval, and fast-track dwell time. Concurrently, it enhances the rescue success rate (proportion of successfully stabilized patients). These demonstrated clinical benefits support its widespread implementation in stroke emergency systems. Further validation through multicenter high-quality trials is recommended to establish efficacy generalizability.

Clinical trial number: Not applicable.

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来源期刊
BMC Emergency Medicine
BMC Emergency Medicine Medicine-Emergency Medicine
CiteScore
3.50
自引率
8.00%
发文量
178
审稿时长
29 weeks
期刊介绍: BMC Emergency Medicine is an open access, peer-reviewed journal that considers articles on all urgent and emergency aspects of medicine, in both practice and basic research. In addition, the journal covers aspects of disaster medicine and medicine in special locations, such as conflict areas and military medicine, together with articles concerning healthcare services in the emergency departments.
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