Melissa Baker, Rudy Zambrano, Eloise W Stanton, Nima Saboori, Anastasia Artemiev, Joseph Pyun, Michael C Gerling, Zorica Buser
{"title":"升高的糖化血红蛋白水平与颈前路椎间盘切除术和融合术后并发症发生率增加无关。","authors":"Melissa Baker, Rudy Zambrano, Eloise W Stanton, Nima Saboori, Anastasia Artemiev, Joseph Pyun, Michael C Gerling, Zorica Buser","doi":"10.1097/BSD.0000000000001856","DOIUrl":null,"url":null,"abstract":"<p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Objective: </strong>To assess the relationship between preoperative HbA1c and postoperative complications up to 180 days in prediabetic and diabetic patients undergoing anterior cervical discectomy and fusion.</p><p><strong>Summary of background data: </strong>Diabetes mellitus has been associated with an increased complication rate and poor postoperative outcomes in patients undergoing elective spine surgeries, but few publications have fully analyzed the effect of preoperative HbA1c on postoperative complications in the cervical spine.</p><p><strong>Methods: </strong>Patients diagnosed with prediabetes or diabetes who underwent anterior cervical discectomy and fusion between 2018 and 2022. Patients were categorized based on their preoperative HbA1c levels: category I with HbA1c levels from 5% to 6.5%, category II from 6.6% to 8%, and category III>8%. Demographics, preoperative glucose and HbA1c levels, and postoperative complications were collected. Postoperative complications were categorized as revision, dysphagia, wound, and other. Pearson χ2 tests and regression models/analyses were used.</p><p><strong>Results: </strong>The current study included 75 patients. Within 30 days postoperatively, there was 1 patient in category I, 1 in category II, and 2 in category III with documented complications. At 31-90 days, only 1 patient in category III reported a complication. There were no complications 91-180 days postoperatively. There was no statistically significant difference in complication or revision rates among the categories at all postoperative time intervals.</p><p><strong>Conclusions: </strong>In the current study, no statistically significant difference was found between elevated HbA1c level and complication rates between diabetics categorized by HbA1c levels at all postoperative time intervals. Future studies are necessary to develop a multifactorial approach to medical clearance in diabetic patients that qualify for cervical spine surgeries.</p>","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Elevated Levels of Hemoglobin A1C are Not Associated With Increased Complication Rates After Anterior Cervical Discectomy and Fusion.\",\"authors\":\"Melissa Baker, Rudy Zambrano, Eloise W Stanton, Nima Saboori, Anastasia Artemiev, Joseph Pyun, Michael C Gerling, Zorica Buser\",\"doi\":\"10.1097/BSD.0000000000001856\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Objective: </strong>To assess the relationship between preoperative HbA1c and postoperative complications up to 180 days in prediabetic and diabetic patients undergoing anterior cervical discectomy and fusion.</p><p><strong>Summary of background data: </strong>Diabetes mellitus has been associated with an increased complication rate and poor postoperative outcomes in patients undergoing elective spine surgeries, but few publications have fully analyzed the effect of preoperative HbA1c on postoperative complications in the cervical spine.</p><p><strong>Methods: </strong>Patients diagnosed with prediabetes or diabetes who underwent anterior cervical discectomy and fusion between 2018 and 2022. Patients were categorized based on their preoperative HbA1c levels: category I with HbA1c levels from 5% to 6.5%, category II from 6.6% to 8%, and category III>8%. Demographics, preoperative glucose and HbA1c levels, and postoperative complications were collected. Postoperative complications were categorized as revision, dysphagia, wound, and other. Pearson χ2 tests and regression models/analyses were used.</p><p><strong>Results: </strong>The current study included 75 patients. Within 30 days postoperatively, there was 1 patient in category I, 1 in category II, and 2 in category III with documented complications. At 31-90 days, only 1 patient in category III reported a complication. There were no complications 91-180 days postoperatively. There was no statistically significant difference in complication or revision rates among the categories at all postoperative time intervals.</p><p><strong>Conclusions: </strong>In the current study, no statistically significant difference was found between elevated HbA1c level and complication rates between diabetics categorized by HbA1c levels at all postoperative time intervals. Future studies are necessary to develop a multifactorial approach to medical clearance in diabetic patients that qualify for cervical spine surgeries.</p>\",\"PeriodicalId\":10457,\"journal\":{\"name\":\"Clinical Spine Surgery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-09-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Spine Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/BSD.0000000000001856\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Spine Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/BSD.0000000000001856","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Elevated Levels of Hemoglobin A1C are Not Associated With Increased Complication Rates After Anterior Cervical Discectomy and Fusion.
Study design: Retrospective cohort study.
Objective: To assess the relationship between preoperative HbA1c and postoperative complications up to 180 days in prediabetic and diabetic patients undergoing anterior cervical discectomy and fusion.
Summary of background data: Diabetes mellitus has been associated with an increased complication rate and poor postoperative outcomes in patients undergoing elective spine surgeries, but few publications have fully analyzed the effect of preoperative HbA1c on postoperative complications in the cervical spine.
Methods: Patients diagnosed with prediabetes or diabetes who underwent anterior cervical discectomy and fusion between 2018 and 2022. Patients were categorized based on their preoperative HbA1c levels: category I with HbA1c levels from 5% to 6.5%, category II from 6.6% to 8%, and category III>8%. Demographics, preoperative glucose and HbA1c levels, and postoperative complications were collected. Postoperative complications were categorized as revision, dysphagia, wound, and other. Pearson χ2 tests and regression models/analyses were used.
Results: The current study included 75 patients. Within 30 days postoperatively, there was 1 patient in category I, 1 in category II, and 2 in category III with documented complications. At 31-90 days, only 1 patient in category III reported a complication. There were no complications 91-180 days postoperatively. There was no statistically significant difference in complication or revision rates among the categories at all postoperative time intervals.
Conclusions: In the current study, no statistically significant difference was found between elevated HbA1c level and complication rates between diabetics categorized by HbA1c levels at all postoperative time intervals. Future studies are necessary to develop a multifactorial approach to medical clearance in diabetic patients that qualify for cervical spine surgeries.
期刊介绍：
Clinical Spine Surgery is the ideal journal for the busy practicing spine surgeon or trainee, as it is the only journal necessary to keep up to date with new clinical research and surgical techniques. Readers get to watch leaders in the field debate controversial topics in a new controversies section, and gain access to evidence-based reviews of important pathologies in the systematic reviews section. The journal features a surgical technique complete with a video, and a tips and tricks section that allows surgeons to review the important steps prior to a complex procedure.
Clinical Spine Surgery provides readers with primary research studies, specifically level 1, 2 and 3 studies, ensuring that articles that may actually change a surgeon’s practice will be read and published. Each issue includes a brief article that will help a surgeon better understand the business of healthcare, as well as an article that will help a surgeon understand how to interpret increasingly complex research methodology. Clinical Spine Surgery is your single source for up-to-date, evidence-based recommendations for spine care.
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