{"title":"与算法赛跑:利用包容性人工智能作为大脑健康的反种族主义工具","authors":"Victor Ekuta","doi":"10.1111/cts.70364","DOIUrl":null,"url":null,"abstract":"<p>Artificial intelligence (AI) is transforming medicine, including neurology and mental health. Yet without equity-centered design, AI risks reinforcing systemic racism. This article explores how algorithmic bias and phenotypic exclusion disproportionately affect marginalized communities in brain health. Drawing on lived experience and scientific evidence, the essay outlines five design principles—centered on inclusion, transparency, and accountability—to ensure AI promotes equity. By reimagining AI as a tool for justice, we can reshape translational science to serve all populations.</p>","PeriodicalId":50610,"journal":{"name":"Cts-Clinical and Translational Science","volume":"18 10","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ascpt.onlinelibrary.wiley.com/doi/epdf/10.1111/cts.70364","citationCount":"0","resultStr":"{\"title\":\"Racing Against the Algorithm: Leveraging Inclusive AI as an Antiracist Tool for Brain Health\",\"authors\":\"Victor Ekuta\",\"doi\":\"10.1111/cts.70364\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Artificial intelligence (AI) is transforming medicine, including neurology and mental health. Yet without equity-centered design, AI risks reinforcing systemic racism. This article explores how algorithmic bias and phenotypic exclusion disproportionately affect marginalized communities in brain health. Drawing on lived experience and scientific evidence, the essay outlines five design principles—centered on inclusion, transparency, and accountability—to ensure AI promotes equity. By reimagining AI as a tool for justice, we can reshape translational science to serve all populations.</p>\",\"PeriodicalId\":50610,\"journal\":{\"name\":\"Cts-Clinical and Translational Science\",\"volume\":\"18 10\",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ascpt.onlinelibrary.wiley.com/doi/epdf/10.1111/cts.70364\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cts-Clinical and Translational Science\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://ascpt.onlinelibrary.wiley.com/doi/10.1111/cts.70364\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cts-Clinical and Translational Science","FirstCategoryId":"3","ListUrlMain":"https://ascpt.onlinelibrary.wiley.com/doi/10.1111/cts.70364","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Racing Against the Algorithm: Leveraging Inclusive AI as an Antiracist Tool for Brain Health
Artificial intelligence (AI) is transforming medicine, including neurology and mental health. Yet without equity-centered design, AI risks reinforcing systemic racism. This article explores how algorithmic bias and phenotypic exclusion disproportionately affect marginalized communities in brain health. Drawing on lived experience and scientific evidence, the essay outlines five design principles—centered on inclusion, transparency, and accountability—to ensure AI promotes equity. By reimagining AI as a tool for justice, we can reshape translational science to serve all populations.
期刊介绍:
Clinical and Translational Science (CTS), an official journal of the American Society for Clinical Pharmacology and Therapeutics, highlights original translational medicine research that helps bridge laboratory discoveries with the diagnosis and treatment of human disease. Translational medicine is a multi-faceted discipline with a focus on translational therapeutics. In a broad sense, translational medicine bridges across the discovery, development, regulation, and utilization spectrum. Research may appear as Full Articles, Brief Reports, Commentaries, Phase Forwards (clinical trials), Reviews, or Tutorials. CTS also includes invited didactic content that covers the connections between clinical pharmacology and translational medicine. Best-in-class methodologies and best practices are also welcomed as Tutorials. These additional features provide context for research articles and facilitate understanding for a wide array of individuals interested in clinical and translational science. CTS welcomes high quality, scientifically sound, original manuscripts focused on clinical pharmacology and translational science, including animal, in vitro, in silico, and clinical studies supporting the breadth of drug discovery, development, regulation and clinical use of both traditional drugs and innovative modalities.