I. V. Fadeeva, A. B. Mikhailova, G. A. Davidova, L. I. Akhmetov, O. S. Antonova, K. K. Churakova, I. I. Selezneva
{"title":"聚乙烯吡咯烷酮与海藻酸钠及双（锰锶）取代磷酸三钙制备的医用复合多孔材料","authors":"I. V. Fadeeva, A. B. Mikhailova, G. A. Davidova, L. I. Akhmetov, O. S. Antonova, K. K. Churakova, I. I. Selezneva","doi":"10.1134/S2075113325701497","DOIUrl":null,"url":null,"abstract":"<p>Porous composite materials have been developed with a matrix composed of a mixture of polyvinylpyrrolidone (PVP) and sodium alginate (ALG), in which ceramic particles of double (manganese- and strontium)-substituted tricalcium phosphate (TCP) are distributed. X-ray diffraction analysis (XRD) demonstrated that the main crystalline phase of the (manganese and strontium)-substituted TCP is whitlockite. In vitro studies revealed that all tested materials are not adhesive to cells and exhibit no cytotoxic or inhibitory effects on them. The porous composite materials characterized by a high rate of bioreabsorption of ceramic particles and a strong potential for antibacterial activity and osteoinductive properties due to ion diffusion and changes in the surface layer properties can be used in reconstructive surgery for the restoration of bone tissue function.</p>","PeriodicalId":586,"journal":{"name":"Inorganic Materials: Applied Research","volume":"16 5","pages":"1404 - 1409"},"PeriodicalIF":0.3000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Composite Porous Materials Made of Polyvinylpyrrolidone and Sodium Alginate and Double (Manganese and Strontium)-Substituted Tricalcium Phosphate for Medicine\",\"authors\":\"I. V. Fadeeva, A. B. Mikhailova, G. A. Davidova, L. I. Akhmetov, O. S. Antonova, K. K. Churakova, I. I. Selezneva\",\"doi\":\"10.1134/S2075113325701497\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Porous composite materials have been developed with a matrix composed of a mixture of polyvinylpyrrolidone (PVP) and sodium alginate (ALG), in which ceramic particles of double (manganese- and strontium)-substituted tricalcium phosphate (TCP) are distributed. X-ray diffraction analysis (XRD) demonstrated that the main crystalline phase of the (manganese and strontium)-substituted TCP is whitlockite. In vitro studies revealed that all tested materials are not adhesive to cells and exhibit no cytotoxic or inhibitory effects on them. The porous composite materials characterized by a high rate of bioreabsorption of ceramic particles and a strong potential for antibacterial activity and osteoinductive properties due to ion diffusion and changes in the surface layer properties can be used in reconstructive surgery for the restoration of bone tissue function.</p>\",\"PeriodicalId\":586,\"journal\":{\"name\":\"Inorganic Materials: Applied Research\",\"volume\":\"16 5\",\"pages\":\"1404 - 1409\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganic Materials: Applied Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S2075113325701497\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganic Materials: Applied Research","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S2075113325701497","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Composite Porous Materials Made of Polyvinylpyrrolidone and Sodium Alginate and Double (Manganese and Strontium)-Substituted Tricalcium Phosphate for Medicine
Porous composite materials have been developed with a matrix composed of a mixture of polyvinylpyrrolidone (PVP) and sodium alginate (ALG), in which ceramic particles of double (manganese- and strontium)-substituted tricalcium phosphate (TCP) are distributed. X-ray diffraction analysis (XRD) demonstrated that the main crystalline phase of the (manganese and strontium)-substituted TCP is whitlockite. In vitro studies revealed that all tested materials are not adhesive to cells and exhibit no cytotoxic or inhibitory effects on them. The porous composite materials characterized by a high rate of bioreabsorption of ceramic particles and a strong potential for antibacterial activity and osteoinductive properties due to ion diffusion and changes in the surface layer properties can be used in reconstructive surgery for the restoration of bone tissue function.
期刊介绍：
Inorganic Materials: Applied Research contains translations of research articles devoted to applied aspects of inorganic materials. Best articles are selected from four Russian periodicals: Materialovedenie, Perspektivnye Materialy, Fizika i Khimiya Obrabotki Materialov, and Voprosy Materialovedeniya and translated into English. The journal reports recent achievements in materials science: physical and chemical bases of materials science; effects of synergism in composite materials; computer simulations; creation of new materials (including carbon-based materials and ceramics, semiconductors, superconductors, composite materials, polymers, materials for nuclear engineering, materials for aircraft and space engineering, materials for quantum electronics, materials for electronics and optoelectronics, materials for nuclear and thermonuclear power engineering, radiation-hardened materials, materials for use in medicine, etc.); analytical techniques; structure–property relationships; nanostructures and nanotechnologies; advanced technologies; use of hydrogen in structural materials; and economic and environmental issues. The journal also considers engineering issues of materials processing with plasma, high-gradient crystallization, laser technology, and ultrasonic technology. Currently the journal does not accept direct submissions, but submissions to one of the source journals is possible.
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