早期巴雷特瘤的内镜治疗-西方观点。

IF 3.6 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Digestion Pub Date : 2025-09-22 DOI:10.1159/000548561
Edward Young, Joseph Fantasia, Eugene Phan, Rajvinder Singh
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引用次数: 0

摘要

背景:巴雷特食管(BE)是唯一确定的食管腺癌的前兆,东西方在其流行病学和治疗方面存在显著差异。摘要:本综述基于结构化的文献检索,探讨了内镜治疗的主要分歧:强调西方强调使用射频消融等消融技术的根除治疗,与东方专业的先进切除技术(包括内镜下粘膜剥离)形成对比。关键信息:尽管改善了患者的预后,但仍然存在重大挑战,包括可变的监测方案,关于非发育不良BE和低级别发育不良的争议,以及复发性疾病的最佳策略。随着胃食管反流病和长段BE在东方的患病率上升,以及西方对内镜下粘膜剥离的熟练程度提高,这些曾经截然不同的方法正准备融合。随着这些治疗模式的结合,患者和临床医生都将受益于更有效、更有针对性的护理和更好的长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic treatment for early Barrett's neoplasia - a Western perspective.

Background: Barrett's oesophagus (BE) is the sole established precursor to oesophageal adenocarcinoma, with striking contrasts in its epidemiology and management between the East and the West.

Summary: This review, based on a structured literature search, examines the key divergences in endoscopic management: highlighting the Western emphasis on eradication therapy using ablation techniques such as radiofrequency ablation, contrasted with the Eastern expertise in advanced resection techniques including endoscopic submucosal dissection.

Key messages: Despite improving patient outcomes, significant challenges remain, including variable surveillance protocols, controversies regarding non-dysplastic BE and low-grade dysplasia, and optimal strategies for recurrent disease. As gastroesophageal reflux disease and long-segment BE rise in prevalence in the East, and Western proficiency in endoscopic submucosal dissection grows, these once-distinct approaches are poised to converge. As these treatment paradigms align, patients and clinicians alike stand to benefit from more effective, tailored care and better long-term outcomes.

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来源期刊
Digestion
Digestion 医学-胃肠肝病学
CiteScore
7.90
自引率
0.00%
发文量
39
审稿时长
6-12 weeks
期刊介绍: ''Digestion'' concentrates on clinical research reports: in addition to editorials and reviews, the journal features sections on Stomach/Esophagus, Bowel, Neuro-Gastroenterology, Liver/Bile, Pancreas, Metabolism/Nutrition and Gastrointestinal Oncology. Papers cover physiology in humans, metabolic studies and clinical work on the etiology, diagnosis, and therapy of human diseases. It is thus especially cut out for gastroenterologists employed in hospitals and outpatient units. Moreover, the journal''s coverage of studies on the metabolism and effects of therapeutic drugs carries considerable value for clinicians and investigators beyond the immediate field of gastroenterology.
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