美国中西部脑瘫的特点。

IF 3.9 2区 医学 Q1 CLINICAL NEUROLOGY
Susie Kim, Kelsey Steffen, Lauren Gottschalk-Henneberry, Jennifer Miros, Amy Robichaux-Viehoever, Karen Taca, Bhooma R Aravamuthan
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引用次数: 0

摘要

目的:脑瘫(CP)是世界上最常见的终身运动障碍。然而,有关CP在美国如何表现的数据有限。我们的目的是描述和确定影响美国中西部大量年轻CP患者功能结局的因素。方法:我们将护理人员和面向临床医生的标准化数据输入整合到三级保健CP中心(https://bit.ly/CP-Intake-Methodology)的常规临床护理中。我们提取了在2023年3月22日至2023年12月28日期间被ICD10诊断为CP的人的数据,并用它来描述CP特征,并确定影响5岁时行走、口服喂养和说话几率的因素。结果:在686例ICD10诊断为CP的独特个体中,663例(97%)有护理人员和临床输入的数据,其中633例有临床确诊的CP诊断(平均年龄9.1岁,男性53.4%,白人78.5%)。常见的有四肢瘫痪(288/613,47.0%)、痉挛和肌张力障碍(257/632,40.7%)、疼痛(230/629,36.6%)、睡眠不良(190/629,30.0%)、焦虑(157/633,24.8%)、独立行走(368/633,58.1%)、口食安全(288/578,55.9%)、言语可理解(249/584,42.6%)和/或需要抗癫痫药物(268/633,42.3%)。皮质灰质损伤、初始重症监护时间和CP病因影响行走、口服喂养和言语的几率(二元逻辑回归,p)解释:注意到大多数CP的人口数据来自美国以外,分析这一详细的美国数据集可能有助于更好地为美国CP患者共存条件的预后和临床筛查提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characteristics of Cerebral Palsy in the Midwestern US.

Objective: Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.

Methods: We integrated caregiver and clinician-facing standardized data entry into routine clinical care at a tertiary care CP center (https://bit.ly/CP-Intake-Methodology). We extracted this data for people with an ICD10 diagnosis of CP seen between March 22, 2023 and December 28, 2023 and used it to describe CP characteristics and determine factors affecting the odds of walking, oral feeding, and speech by Age 5.

Results: Of 686 unique individuals with an ICD10 diagnosis of CP, 663 (97%) had caregiver- and clinician-entered data, of whom 633 had a clinician-confirmed CP diagnosis (mean age 9.1, 53.4% Male, 78.5% White). It was common to have quadriplegia (288/613, 47.0%), both spasticity and dystonia (257/632, 40.7%), pain (230/629, 36.6%), poor sleep (190/629, 30.0%), anxiety (157/633, 24.8%), walk independently (368/633, 58.1%), eat food and drink safely by mouth (288/578, 55.9%), produce understandable speech (249/584, 42.6%), and/or require anti-seizure medications (268/633, 42.3%). Cortical gray matter injury, initial critical care stay duration, and CP etiology affected the odds of walking, oral feeding, and speech (binary logistic regression, p < 0.001).

Interpretation: Noting that most population data on CP is from outside of the US, analysis of this detailed American dataset may help better inform prognostication and clinical screening for co-existing conditions in people with CP in the US.

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来源期刊
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology Medicine-Neurology (clinical)
CiteScore
9.10
自引率
1.90%
发文量
218
审稿时长
8 weeks
期刊介绍: Annals of Clinical and Translational Neurology is a peer-reviewed journal for rapid dissemination of high-quality research related to all areas of neurology. The journal publishes original research and scholarly reviews focused on the mechanisms and treatments of diseases of the nervous system; high-impact topics in neurologic education; and other topics of interest to the clinical neuroscience community.
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