牙源性感染:c反应蛋白作为感染严重程度和住院轨迹的预测因子

Mohamed Naqeeb , Kai Lee , Sipho Simon Nhongo
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引用次数: 0

摘要

目的确定治疗前血清c反应蛋白浓度作为严重牙源性感染(如深颈间隙受累或全身损害)住院患者总住院时间(LOS)、重症监护病房(ICU)入院和重返手术室(RTT)的预测因子的效用。本回顾性研究分析了2012年至2020年间在Western Health口腔颌面外科接受全身麻醉引流的206例患者。收集的数据包括患者人口统计学、入院时CRP、临床特征和结局(ICU入院、LOS和RTT)。结果CRP水平升高(≥150mg /L)与住院LOS增加(β: 2.831天)、ICU住院率增加(OR: 5.504)、再引流可能性增加(OR: 13.53)显著相关。本研究基于入院时CRP测量建立了新的LOS预测模型:LOS = 0.023 x CRP +1.77。结论CRP水平升高表明LOS延长的风险增加,RTT需求增加,ICU入院率增加。这些发现可以支持CRP在患者轨迹、资源分配和急诊患者管理的预测模型中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Odontogenic infections: C-reactive protein as a predictor of infection severity and inpatient trajectory

Objectives

To determine the utility of serum C-reactive protein concentration prior to treatment as a predictor of total length of hospital stay (LOS), intensive care unit (ICU) admission, and return to theatre (RTT) for inpatients with severe odontogenic infections (such as deep neck space involvement or systemic compromise).

Study design

This retrospective study analysed 206 patients admitted for surgical drainage under general anaesthesia at the Western Health Oral and Maxillofacial unit between 2012 and 2020. Data collected included patient demographics, CRP on admission, clinical features and outcomes (ICU admission, LOS and RTT).

Results

Elevated CRP levels (≥150 mg/L) were significantly associated with increased hospital LOS (β: 2.831 days), higher ICU admission rates (OR: 5.504), and a greater likelihood of re-drainage (OR: 13.53). The study developed a new predictive model for LOS based on CRP measurement on admission: LOS = 0.023 x CRP +1.77.

Conclusion

Elevated CRP levels indicate higher risks of prolonged LOS, increased need for RTT and higher rates of ICU admissions. These findings can support the use of CRP in predictive modelling for patient trajectory, resource allocation and emergency patient management.
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