生物医学用镁合金的选择性激光熔化:显微结构到临床转化

IF 6.6 2区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY
Mohamad Zaki Hassan , A.N. Aufa , Zbigniew Brytan , Tomasz Tanski , James Ren , Janusz Mazurkiewicz , Mohd Shahrir Mohd Sani , Zarini Ismail
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引用次数: 0

摘要

选择性激光熔化(SLM)已成为一种具有竞争力的增材制造(AM)技术,用于生产具有复杂形状的生物医学用途的镁(Mg)合金植入物。镁合金具有生物可降解性和耐久性,可与真骨媲美。然而,SLM中的快速凝固会在调节晶粒系统、气孔和裂纹方面产生问题,所有这些都会极大地影响最终部件的强度和腐蚀性能。本文综述了最近在澄清加工环境、微观结构特征及其对生物因素的影响之间的联系方面的进展。体外和体内研究对于评估SLM-Mg合金在生理环境中的降解行为、细胞相容性和生物反应至关重要。它还检查缺陷缓解策略和后处理处理。未来的方向包括建立强化合金系统的策略,优化过程监控,以及改进表征技术的实施,以增强SLM mg基植入物的临床转化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Selective laser melting of magnesium alloys for biomedical applications: Microstructure to clinical translation
Selective Laser Melting (SLM) has emerged as a competitive additive manufacturing (AM) technique for producing magnesium (Mg) alloy implants with complicated shapes intended for biomedical usages. Mg alloys are appealing because of their biodegradability and durability, which are comparable to those of real bone. However, a rapid solidification in SLM creates issues in regulating the grain system, pores, and cracking, all of which considerably affect the strength and corrosion performances of the final components. This review highlights recent progress in clarifying the connections among processing settings, microstructural features, and their effects on biological elements. In vitro and in vivo studies are crucial for assessing the degradation behaviour, cytocompatibility, and biological reaction of SLM-Mg alloys in physiological environments. It also examines defect mitigation strategies and post-processing treatments. Future directions include the establishment of strategies to enhance alloy systems, the optimisation of process monitoring, and the implementation of improved characterisation techniques to enhance the clinical translation of SLM Mg-based implants.
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来源期刊
Journal of Materials Research and Technology-Jmr&t
Journal of Materials Research and Technology-Jmr&t Materials Science-Metals and Alloys
CiteScore
8.80
自引率
9.40%
发文量
1877
审稿时长
35 days
期刊介绍: The Journal of Materials Research and Technology is a publication of ABM - Brazilian Metallurgical, Materials and Mining Association - and publishes four issues per year also with a free version online (www.jmrt.com.br). The journal provides an international medium for the publication of theoretical and experimental studies related to Metallurgy, Materials and Minerals research and technology. Appropriate submissions to the Journal of Materials Research and Technology should include scientific and/or engineering factors which affect processes and products in the Metallurgy, Materials and Mining areas.
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