套细胞淋巴瘤伴嗜酸性细胞增多：1例报告及文献复习。

IF 3.1 4区医学 Q3 ONCOLOGY

Tumori Pub Date : 2025-09-20 DOI:10.1177/03008916251362124

Xianghui Liu, Tianjie Han, Yue Ma, Zhe Yu

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引用次数: 0

摘要

导论：反应性嗜酸性粒细胞增多已被报道在几种血液系统恶性肿瘤中，包括霍奇金淋巴瘤、t细胞淋巴瘤/白血病和急性白血病。然而，嗜酸性粒细胞增多与b细胞非霍奇金淋巴瘤相关的报道很少。套细胞淋巴瘤是起源于成熟B细胞的非霍奇金淋巴瘤的一个亚类。在本文中，我们首次报告一例套细胞淋巴瘤伴嗜酸性细胞增多症。病例描述：一名69岁男性患者被诊断为套细胞淋巴瘤伴嗜酸性粒细胞增多，排除了嗜酸性粒细胞增多的常见继发原因。免疫化疗后，患者淋巴瘤缓解，嗜酸性粒细胞水平恢复正常。结论：本病例可能增加了关于b细胞非霍奇金淋巴瘤嗜酸性粒细胞增多的有限文献。本研究的局限性包括缺乏扩大的基因面板检测来确认嗜酸性粒细胞克隆或t细胞克隆，未测量IL-5水平，以及病例报告的固有约束。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mantle cell lymphoma with hypereosinophilia: A case report and review of the literature.

Introdution: Reactive eosinophilia has been reported in several hematological malignancies, including Hodgkin-s lymphoma, T-cell lymphoma/leukemia, and acute leukemia. However, eosinophilia associated with B-cell non-Hodgkin-s lymphoma is rarely reported. Mantle cell lymphoma is a subcategory of non-Hodgkin-s lymphoma originated from mature B cells. In this article, we report for the first time a case of mantle cell lymphoma with hypereosinophilia.

Case description: A 69-year-old male patient was diagnosed with mantle cell lymphoma accompanied by eosinophilia, with common secondary causes of eosinophilia ruled out. Following immunochemotherapy, the patient achieved lymphoma remission, and eosinophil levels returned to normal.

Conclusion: This case potentially adds to the limited body of literature on eosinophilia in B-cell non-Hodgkin lymphoma. The limitations of this study include the absence of expanded genetic panel testing to confirm eosinophil clonality or T-cell clonality, unmeasured IL-5 levels, and inherent constraints of case reports.

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来源期刊

Tumori 医学-肿瘤学

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Tumori Journal covers all aspects of cancer science and clinical practice with a strong focus on prevention, translational medicine and clinically relevant reports. We invite the publication of randomized trials and reports on large, consecutive patient series that investigate the real impact of new techniques, drugs and devices inday-to-day clinical practice.