组织灌注是围手术期血流动力学干预的最终目标。

IF 5.1 2区医学 Q1 ANESTHESIOLOGY

Journal of Clinical Anesthesia Pub Date : 2025-09-18 DOI:10.1016/j.jclinane.2025.112009

Zbigniew Putowski , Jan Bakker , Eduardo Kattan , Glenn Hernández , Hafid Ait-Oufella , Wojciech Szczeklik , Philippe Guerci

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引用次数: 0

摘要

这篇观点文章探讨了整体血流动力学参数和组织灌注之间的复杂关系，强调了使用宏观血流动力学指标作为组织水平氧输送指标的局限性。本文的主要主题包括组织灌注的生理决定因素，麻醉对灌注动力学的影响，以及血流动力学干预在优化灌注中的作用。此外，我们探讨了组织灌注监测在围手术期的应用，强调了其指导个体化治疗的潜力。通过解决这些相互关联的因素，我们主张进行进一步的研究，以评估在当前方案中添加灌注引导策略是否可以提高患者的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Tissue perfusion as the ultimate target of hemodynamic interventions in the perioperative period

This point-of-view article examines the complex relationship between global hemodynamic parameters and tissue perfusion, emphasizing the limitations of using macrohemodynamic metrics as proxies for tissue-level oxygen delivery. Key topics of the paper include the physiological determinants of tissue perfusion, the influence of anesthesia on perfusion dynamics, and the role of hemodynamic interventions in optimizing perfusion. Furthermore, we explore the application of tissue perfusion monitoring in the perioperative setting, highlighting its potential to guide individualized therapies. By addressing these interconnected factors, we advocate for further research to evaluate whether adding perfusion-guided strategies to current protocols can enhance patient outcomes.

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来源期刊

Journal of Clinical Anesthesia 医学-麻醉学

CiteScore

7.40

自引率

4.50%

发文量

346

审稿时长

23 days

期刊介绍： The Journal of Clinical Anesthesia (JCA) addresses all aspects of anesthesia practice, including anesthetic administration, pharmacokinetics, preoperative and postoperative considerations, coexisting disease and other complicating factors, cost issues, and similar concerns anesthesiologists contend with daily. Exceptionally high standards of presentation and accuracy are maintained. The core of the journal is original contributions on subjects relevant to clinical practice, and rigorously peer-reviewed. Highly respected international experts have joined together to form the Editorial Board, sharing their years of experience and clinical expertise. Specialized section editors cover the various subspecialties within the field. To keep your practical clinical skills current, the journal bridges the gap between the laboratory and the clinical practice of anesthesiology and critical care to clarify how new insights can improve daily practice.