{"title":"增强脑卒中幸存者认知障碍的社会参与：一项随机对照试验。","authors":"Shih-Pin Hsu, Te-Hsun Hung, Yen-Nung Lin, Jiunn-Horng Kang, Der-Sheng Han, Valeria Chiu, Tsan-Hon Liou, Yi-Hsuan Wu, Peng-Sheng Ni, Elizabeth R Skidmore, Feng-Hang Chang","doi":"10.1161/JAHA.125.042295","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Returning to societal participation is an important goal for stroke survivors, but evidence for effective rehabilitation remains inconclusive. This study evaluated the efficacy of participation-focused strategy training in improving poststroke participation among community-dwelling survivors with cognitive impairments.</p><p><strong>Methods: </strong>This multicenter, randomized trial enrolled stroke survivors with executive function impairments between January 2019 and March 2023. Participants received either strategy training (n=96) or an attention-control intervention (n=99) in 12 to 15 sessions over 8 weeks. The primary outcome was the postintervention change in participation across productivity, social, and community domains from the baseline, measured by the Participation Measure-3 Domains, 4 Dimensions. Secondary outcomes included changes in activity performance, self-efficacy, and global cognition from baseline.</p><p><strong>Results: </strong>Eligible 195 participants were included in the intention-to-treat analysis (64 women, 32.8%; median [interquartile range] age: 62 [52-68] years). After adjusting for baseline primary outcome, stroke severity, and dose of regular rehabilitation, the strategy training group showed greater improvements in productivity and social participation compared with the control group (adjusted mean difference between groups [95% CI]: 7.89 [2.61-13.16] (<i>P</i>=0.004) and 0.29 [0.08-0.51] (<i>P</i>=0.009), respectively) from baseline to postintervention. These effects remained without adjustment, but did not persist at 3-month follow-up. No significant between-group differences were observed for any other outcomes.</p><p><strong>Conclusions: </strong>Participation-focused strategy training significantly improved productivity and social participation among enrolled stroke survivors compared with the control intervention postintervention. Further research is warranted to confirm these findings in the oldest survivors and to explore approaches for enhancing the long-term benefits of strategy training.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT03792061.</p>","PeriodicalId":54370,"journal":{"name":"Journal of the American Heart Association","volume":" ","pages":"e042295"},"PeriodicalIF":5.3000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancing Societal Participation for Stroke Survivors With Cognitive Impairments: A Randomized Controlled Trial.\",\"authors\":\"Shih-Pin Hsu, Te-Hsun Hung, Yen-Nung Lin, Jiunn-Horng Kang, Der-Sheng Han, Valeria Chiu, Tsan-Hon Liou, Yi-Hsuan Wu, Peng-Sheng Ni, Elizabeth R Skidmore, Feng-Hang Chang\",\"doi\":\"10.1161/JAHA.125.042295\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Returning to societal participation is an important goal for stroke survivors, but evidence for effective rehabilitation remains inconclusive. This study evaluated the efficacy of participation-focused strategy training in improving poststroke participation among community-dwelling survivors with cognitive impairments.</p><p><strong>Methods: </strong>This multicenter, randomized trial enrolled stroke survivors with executive function impairments between January 2019 and March 2023. Participants received either strategy training (n=96) or an attention-control intervention (n=99) in 12 to 15 sessions over 8 weeks. The primary outcome was the postintervention change in participation across productivity, social, and community domains from the baseline, measured by the Participation Measure-3 Domains, 4 Dimensions. Secondary outcomes included changes in activity performance, self-efficacy, and global cognition from baseline.</p><p><strong>Results: </strong>Eligible 195 participants were included in the intention-to-treat analysis (64 women, 32.8%; median [interquartile range] age: 62 [52-68] years). After adjusting for baseline primary outcome, stroke severity, and dose of regular rehabilitation, the strategy training group showed greater improvements in productivity and social participation compared with the control group (adjusted mean difference between groups [95% CI]: 7.89 [2.61-13.16] (<i>P</i>=0.004) and 0.29 [0.08-0.51] (<i>P</i>=0.009), respectively) from baseline to postintervention. These effects remained without adjustment, but did not persist at 3-month follow-up. No significant between-group differences were observed for any other outcomes.</p><p><strong>Conclusions: </strong>Participation-focused strategy training significantly improved productivity and social participation among enrolled stroke survivors compared with the control intervention postintervention. Further research is warranted to confirm these findings in the oldest survivors and to explore approaches for enhancing the long-term benefits of strategy training.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT03792061.</p>\",\"PeriodicalId\":54370,\"journal\":{\"name\":\"Journal of the American Heart Association\",\"volume\":\" \",\"pages\":\"e042295\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2025-10-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the American Heart Association\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1161/JAHA.125.042295\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Heart Association","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1161/JAHA.125.042295","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/19 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Enhancing Societal Participation for Stroke Survivors With Cognitive Impairments: A Randomized Controlled Trial.
Background: Returning to societal participation is an important goal for stroke survivors, but evidence for effective rehabilitation remains inconclusive. This study evaluated the efficacy of participation-focused strategy training in improving poststroke participation among community-dwelling survivors with cognitive impairments.
Methods: This multicenter, randomized trial enrolled stroke survivors with executive function impairments between January 2019 and March 2023. Participants received either strategy training (n=96) or an attention-control intervention (n=99) in 12 to 15 sessions over 8 weeks. The primary outcome was the postintervention change in participation across productivity, social, and community domains from the baseline, measured by the Participation Measure-3 Domains, 4 Dimensions. Secondary outcomes included changes in activity performance, self-efficacy, and global cognition from baseline.
Results: Eligible 195 participants were included in the intention-to-treat analysis (64 women, 32.8%; median [interquartile range] age: 62 [52-68] years). After adjusting for baseline primary outcome, stroke severity, and dose of regular rehabilitation, the strategy training group showed greater improvements in productivity and social participation compared with the control group (adjusted mean difference between groups [95% CI]: 7.89 [2.61-13.16] (P=0.004) and 0.29 [0.08-0.51] (P=0.009), respectively) from baseline to postintervention. These effects remained without adjustment, but did not persist at 3-month follow-up. No significant between-group differences were observed for any other outcomes.
Conclusions: Participation-focused strategy training significantly improved productivity and social participation among enrolled stroke survivors compared with the control intervention postintervention. Further research is warranted to confirm these findings in the oldest survivors and to explore approaches for enhancing the long-term benefits of strategy training.
期刊介绍：
As an Open Access journal, JAHA - Journal of the American Heart Association is rapidly and freely available, accelerating the translation of strong science into effective practice.
JAHA is an authoritative, peer-reviewed Open Access journal focusing on cardiovascular and cerebrovascular disease. JAHA provides a global forum for basic and clinical research and timely reviews on cardiovascular disease and stroke. As an Open Access journal, its content is free on publication to read, download, and share, accelerating the translation of strong science into effective practice.
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