短期正念干预对新诊断肌萎缩侧索硬化症患者情绪、睡眠和生活质量的影响：一项前瞻性研究
IF 4.8
3区 医学
Q1 CLINICAL NEUROLOGY
引用次数: 0
摘要
简介：肌萎缩性侧索硬化症（ALS）是一种毁灭性的进行性神经退行性疾病，会给患者带来严重的痛苦和精神健康问题。许多ALS患者在刚被确诊时对严重的诊断有严重的心理反应。本研究旨在探讨短期正念干预对新近确诊的ALS患者情绪、睡眠和生活质量的影响。方法：这项前瞻性干预研究纳入了新诊断为ALS的患者。参与者接受为期10天的认知训练和音频引导的正念练习，包括呼吸意识和身体扫描。干预的有效性通过几个量表来评估。结果：91例患者最终纳入分析，年龄54.15[10.10]岁，男52例/女39例[57.10%/42.90%]。中文版感知压力量表（CPSS）得分（t = 2.05, P = 0.04）和Epworth嗜睡量表（ESS）得分（Z = -2.03, P = 0.04）显著降低，40项肌萎缩性侧索硬化症评估问卷（ALSAQ40）得分显著升高（Z = -2.93， P）。结论：本研究提示，短暂的正念干预可能是减少抑郁和改善白天嗜睡的潜在方法，同时也可以改善新诊断的ALS患者的生活质量。本文章由计算机程序翻译，如有差异，请以英文原文为准。
Impact of Brief Mindfulness Intervention on Emotions, Sleep and Quality of Life in Patients with Newly Diagnosed Amyotrophic Lateral Sclerosis: A Prospective Study.
Introduction: Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disorder causing significant suffering and mental health problems for patients. Many patients with ALS have a severe psychological reaction to the serious diagnosis when they are first diagnosed. This study aims to investigate the impact of a brief mindfulness intervention on emotions, sleep, and quality of life (QOL) in patients with ALS who have recently been diagnosed.
Methods: This prospective intervention study enrolled patients who had been newly diagnosed with ALS. Participants received cognitive training and audio-led mindfulness exercises involving breathing awareness and body scan sessions for 10 days. The effectiveness of the intervention was evaluated by several scales.
Results: Ninety-one patients (aged 54.15 [10.10] years, 52 male/39 female [57.10%/42.90%]) were finally enrolled in the analysis. The Chinese Version Perceived Stress Scale (CPSS) (t = 2.05, P = 0.04) and Epworth Sleepiness Scale (ESS) (Z = -2.03, P = 0.04) scores significantly decreased, and the 40-item Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ40) significantly increased (Z = -2.93, P < 0.01) following the brief mindfulness intervention. The Patient Health Questionnaire-9 (PHQ-9) (Z = -2.97, P < 0.01) and the 17-Item Hamilton Rating Scale for Depression (HAMD-17) (Z = -3.43, P < 0.01) were significantly reduced in patients with ALS diagnosed with depression. QOL was significantly improved in other patients with ALS (Z = -2.51, P = 0.01).
Conclusion: Our study indicated that a brief mindfulness intervention could be a potential way to reduce depression and improve daytime sleepiness, while also improving the QOL for newly diagnosed patients with ALS.
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来源期刊
Neurology and Therapy
CLINICAL NEUROLOGY-
CiteScore
5.40
自引率
8.10%
发文量
103
审稿时长
6 weeks
期刊介绍：
Aims and Scope
Neurology and Therapy aims to provide reliable and inclusive, rapid publication for all therapy related research for neurological indications, supporting the timely dissemination of research with a global reach, to help advance scientific discovery and support clinical practice.
Neurology and Therapy is an international, open access, peer reviewed, rapid publication journal dedicated to the publication of high-quality clinical (all phases), observational, real-world and health outcomes research around the discovery, development, and use of neurological and psychiatric therapies, (also covering surgery and devices). Studies relating to diagnosis, pharmacoeconomics, public health, quality of life, and patient care, management, and education are also welcomed.
The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, case reports, trial designs, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Neurology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
Rapid Publication
The journal’s rapid publication timelines aim for a peer review decision within 2 weeks of submission. If an article is accepted, it will be published online 3-4 weeks from acceptance. These rapid timelines are achieved through the combination of a dedicated in-house editorial team, who closely manage article workflow, and an extensive Editorial and Advisory Board who assist with rapid peer review. This allows the journal to support the rapid dissemination of research, whilst still providing robust peer review. Combined with the journal’s open access model, this allows for the rapid and efficient communication of the latest research and reviews to support scientific discovery and clinical practice.
Open Access
All articles published by Neurology and Therapy are open access.
Personal Service
The journal’s dedicated in-house editorial team offer a personal “concierge service” meaning that authors will always have a personal point of contact able to update them on the status of their manuscript. The editorial team check all manuscripts to ensure that articles conform to the most recent COPE and ICMJE publishing guidelines. This supports the publication of ethically sound and transparent research. We also encourage pre-submission enquiries and are always happy to provide a confidential assessment of manuscripts.
Digital Features and Plain Language Summaries
Neurology and Therapy offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content. Each article is accompanied by key summary points, giving a time-efficient overview of the content to a wide readership. Articles may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand the scientific content and overall implications of the article. The journal also provides the option to include various types of digital features including animated abstracts, video abstracts, slide decks, audio slides, instructional videos, infographics, podcasts and animations. All additional features are peer reviewed to the same high standard as the article itself. If you consider that your paper would benefit from the inclusion of a digital feature, please let us know. Our editorial team are able to create high-quality slide decks and infographics in-house, and video abstracts through our partner Research Square, and would be happy to assist in any way we can. For further information about digital features, please contact the journal editor (see ‘Contact the Journal’ for email address), and see the ‘Guidelines for digital features and plain language summaries’ document under ‘Submission guidelines’.
For examples of digital features please visit our showcase page https://springerhealthcare.com/expertise/publishing-digital-features/
Publication Fees
Upon acceptance of an article, authors will be required to pay the mandatory Rapid Service Fee of €5250/$6000/£4300. The journal will consider fee discounts and waivers for developing countries and this is decided on a case-by-case basis.
Peer Review Process
Upon submission, manuscripts are assessed by the editorial team to ensure they fit within the aims and scope of the journal and are also checked for plagiarism. All suitable submissions are then subject to a comprehensive single-blind peer review. Reviewers are selected based on their relevant expertise and publication history in the subject area. The journal has an extensive pool of editorial and advisory board members who have been selected to assist with peer review based on the afore-mentioned criteria.
At least two extensive reviews are required to make the editorial decision, with the exception of some article types such as Commentaries, Editorials and Letters which are generally reviewed by one member of the Editorial Board. Where reviews conflict, an Editorial Board Member will be contacted for further advice and a presiding decision. Manuscripts are then either accepted, rejected or authors are required to make major or minor revisions (both reviewer comments and editorial comments may need to be addressed. Once a revised manuscript is re-submitted, it is assessed along with the responses to reviewer comments and if it has been adequately revised, it will be accepted for publication. Accepted manuscripts are then copyedited and typeset by the production team before online publication. Appeals against decisions following peer review are considered on a case-by-case basis and should be sent to the journal editor, and authors are welcome to make rebuttals against individual reviewer comments, if appropriate.
Preprints
We encourage posting of preprints of primary research manuscripts on preprint servers, authors'' or institutional websites, and open communications between researchers whether on community preprint servers or preprint commenting platforms. Posting of preprints is not considered prior publication and will not jeopardize consideration in our journals.
Please see here for further information on preprint sharing: https://www.springer.com/gp/authors-editors/journal-author/journal-author-helpdesk/submission/1302#c16721550
Copyright
Neurology and Therapy is published under the Creative Commons Attribution-Noncommercial License, which allows users to read, copy, distribute, and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited. The author assigns the exclusive right to any commercial use of the article to Springer. For more information about the Creative Commons Attribution-Noncommercial License, click here: http://creativecommons.org/licenses/by-nc/4.0.
Contact
For more information about the journal, including pre-submission enquiries, please contact managing editor Lydia Alborn at lydia.alborn@springer.com.
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