使用富血小板血浆治疗肩袖损伤:临床试验回顾

IF 0.6 4区 医学 Q4 ORTHOPEDICS
Acta Ortopedica Brasileira Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI:10.1590/1413-785220253304e290196
João Paulo Coelho Cintra, Hugo Pinhone Ravagnani, Murillo Augusto Ribeiro do Nascimento, Henrique de Paula Rodrigues Nishimura
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引用次数: 0

摘要

肩袖损伤的发生是由于肩关节的过度使用、创伤或与年龄相关的变性,并因肩峰下病变和解剖学因素而加重。症状包括持续疼痛、活动范围缩小和肌肉无力,影响患者的生活质量。治疗可以是保守或手术,富血小板血浆(PRP)已经成为加速愈合和减少炎症的替代方法。目的是回顾关于使用PRP治疗肩袖损伤的文献。根据以下搜索策略选择PUBMED数据库中最近5年发表的临床试验:(血小板[title]和富血小板[title]和血浆[title])和(旋转体[title]和袖带[title])。对最初的搜索做出回应的13项研究被纳入本综述的样本中。PRP已被证明是治疗肩袖损伤的一种很有前途的替代方法,特别是在短期疼痛和功能方面。然而,其长期疗效及其与皮质类固醇的比较仍存在争议。因此,治疗的选择应个性化,考虑到每个患者的特点和目标。证据水平IV;来自描述性(非实验性)研究或定性方法的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
USE OF PLATELET-RICH PLASMA IN THE TREATMENT OF ROTATOR CUFF INJURIES: REVIEW OF CLINICAL TRIALS.

Rotator cuff injuries occur due to overuse of the shoulder joint, trauma or age-related degeneration, and are aggravated by subacromial lesions and anatomical factors. Symptoms include persistent pain, reduced range of motion and muscle weakness, compromising patients' quality of life. Treatment can be conservative or surgical, and platelet-rich plasma (PRP) has emerged as an alternative to speed up healing and reduce inflammation. The objective was to review the literature on the use of PRP in the treatment of rotator cuff injuries. Clinical trials published in the last 5 years and available in the PUBMED database were selected, based on the following search strategy: (platelet[title] AND rich[title] AND plasma[title]) AND (rotator[title] AND cuff[title]). The 13 studies that responded to the initial search were included in the sample that made up this review. PRP has been shown to be a promising alternative for treating rotator cuff injuries, especially in terms of short-term pain and function. However, its long-term efficacy and its comparison with corticosteroids are still a matter of debate. Therefore, the choice of treatment should be personalized, taking into account the characteristics and goals of each patient. Level of Evidence IV; Evidence from Descriptive (Non-Experimental) Studies or with a Qualitative Approach.

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来源期刊
CiteScore
0.90
自引率
14.30%
发文量
67
审稿时长
25 weeks
期刊介绍: A Revista Acta Ortopédica Brasileira, órgão oficial do Departamento de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo (DOT/FMUSP), é publicada bimestralmente em seis edições ao ano (jan/fev, mar/abr, maio/jun, jul/ago, set/out e nov/dez) com versão em inglês disponível nos principais indexadores nacionais e internacionais e instituições de ensino do Brasil. Sendo hoje reconhecidamente uma importante contribuição para os especialistas da área com sua seriedade e árduo trabalho para as indexações já conquistadas.
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