Brock E Polnaszek, Jessica Chen, Rodolfo Fernandez-Criado, Anna Palatnik, Susan Cohen, Methodius G Tuuli, Adam K Lewkowitz
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引用次数: 0
摘要
背景:这项预先指定的随机对照试验分析比较了有羊膜输注和没有羊膜输注的参与者之间的胎儿电子监测模式。方法:来自父母随机试验的数据包括26例有胎儿神经损伤危险因素的足月单胎未分娩参与者。对于这一次要分析,主要结果是总减速面积-一种预测新生儿酸血症和发病率的模式。次要结局包括胎儿电子监测模式(如变异性)。结果:无羊膜输注组与羊膜输注组总减速面积无差异(28 550 [8800-57 400]mm²[IQR] vs 31 500 [21 700-47 785]mm²[IQR], P = .84)。羊膜输注的具体次要结局不同。结论:这些结果强调需要前瞻性数据来确定降低发病率的最佳羊膜输注给药技术。
Electronic Fetal Monitoring Patterns With and Without Continuous Amnioinfusion.
Background: This pre-specified analysis of a randomized controlled trial compared electronic fetal monitoring patterns among participants with and without amnioinfusion.
Methods: Data from the parent randomized trial included 26 term singleton nulliparous participants who developed risk factors for fetal neurologic injury. For this secondary analysis, the primary outcome was total deceleration area-a pattern predictive of neonatal acidemia and morbidity. Secondary outcomes included electronic fetal monitoring patterns (eg, variability).
Results: There were no differences in total deceleration area between the no amnioinfusion group and the amnioinfusion group (28 550 [8800-57 400] mm² [IQR] vs 31 500 [21 700-47 785] mm² [IQR], respectively; P = .84). Specific secondary outcomes differed by amnioinfusion.
Conclusions: These results highlight the need for prospective data to identify the optimal amnioinfusion administration technique that reduces morbidity.