探讨BPPV、甲状腺功能减退和代谢合并症之间的关系:一项回顾性病例对照研究。

IF 3
Journal of multimorbidity and comorbidity Pub Date : 2025-09-13 eCollection Date: 2025-01-01 DOI:10.1177/26335565251371254
Rachael Arabian, Antonio Vintimilla
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引用次数: 0

摘要

背景与目的:良性阵发性体位性眩晕(BPPV)是眩晕的主要原因,与骨质疏松、维生素D缺乏和更广泛的代谢功能障碍有一定的相关性。新出现的证据表明BPPV可能与前庭系统以外的全身性疾病有关。然而,有限的研究探讨了BPPV患者是否有甲状腺功能减退、糖尿病(DM)、高血压(HTN)或骨质疏松症的发生率增加。本研究旨在探讨BPPV与甲状腺功能减退、糖尿病(DM)、高血压(HTN)和骨质疏松症之间的关系。研究设计与背景:本研究是一项回顾性病例对照研究,使用来自美国佛罗里达州前庭门诊康复诊所的患者记录。患者和结果:诊断为BPPV的成年人在六个月内被纳入研究。对照数据来自国家卫生统计中心(NCHS)。采用二项逻辑回归计算比值比(ORs)。结果:共分析了140例诊断为BPPV的患者(女性98例,男性42例)。与全国估计相比,BPPV患者患甲状腺功能减退症(OR 2.635, 95% CI 1.260-5.51)和糖尿病(OR 2.28, 95% CI 1.09-4.76)的几率具有统计学意义。没有发现高血压或骨质疏松症的显著相关性。结论:BPPV与甲状腺功能减退、糖尿病均有相关性。这些发现支持了全身代谢和内分泌功能障碍在BPPV病理生理中的作用,并强调了筛查相关合并症的潜在临床价值。进一步的研究是有必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Exploring the association between BPPV, hypothyroidism, and metabolic comorbidities: A retrospective case-control study.

Exploring the association between BPPV, hypothyroidism, and metabolic comorbidities: A retrospective case-control study.

Exploring the association between BPPV, hypothyroidism, and metabolic comorbidities: A retrospective case-control study.

Exploring the association between BPPV, hypothyroidism, and metabolic comorbidities: A retrospective case-control study.

Background & objective: Benign paroxysmal positional vertigo (BPPV) is a leading cause of vertigo and has been loosely associated with osteoporosis, vitamin D deficiency, and broader metabolic dysfunction. Emerging evidence suggests that BPPV may relate to systemic conditions beyond the vestibular system. However, limited research has explored whether individuals with BPPV have increased rates of hypothyroidism, diabetes mellitus (DM), hypertension (HTN), or osteoporosis. The objective of this study was to examine the association between BPPV and hypothyroidism, diabetes mellitus (DM), hypertension (HTN), and osteoporosis.

Study design & setting: This study was a retrospective case-control study using patient records from a vestibular outpatient rehabilitation clinic in Florida, USA.

Patients & outcomes: Adults diagnosed with BPPV over a six-month period were included in the study. Control data was derived from the National Center for Health Statistics (NCHS). Binomial logistic regression was performed to calculate odds ratios (ORs).

Results: A total of 140 individuals diagnosed with BPPV (98 female, 42 male) were analyzed. Patients with BPPV demonstrated statistically significant higher odds of hypothyroidism (OR 2.635, 95% CI 1.260-5.51) and diabetes mellitus (OR 2.28, 95% CI 1.09-4.76) compared to national estimates. No significant associations were found for hypertension or osteoporosis.

Conclusion: An association exists between BPPV and both hypothyroidism and diabetes mellitus. These findings support the role of systemic metabolic and endocrine dysfunction in the pathophysiology of BPPV and highlight the potential clinical value of screening for relevant comorbidities. Further research is warranted.

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