解剖外主动脉搭桥术同时单期手术治疗主动脉缩窄合并心内异常。

IF 0.6 Q3 Medicine
ASIAN CARDIOVASCULAR & THORACIC ANNALS Pub Date : 2025-09-01 Epub Date: 2025-09-15 DOI:10.1177/02184923251376748
Utkarsh Sanghavi, Vikas Vasudeva Rao, Devvrat Desai, Jignesh Kothari
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引用次数: 0

摘要

背景:主动脉缩窄(CoA)是一种先天性疾病,通常需要干预,特别是当它伴有其他心脏内异常时。治疗复杂CoA和相关缺陷的手术方法各不相同,没有普遍接受的标准方法。本研究评估了成人患者从升主动脉到降主动脉的单期解剖外搭桥术的结果,并同时纠正了相关的心内异常。方法回顾性分析了2014年1月至2023年12月期间接受单期解剖外旁路治疗复杂CoA修复的17例成年患者。患者通过右侧解剖外入路行胸主动脉升降分流术,同时纠正相关心脏缺陷。测量的主要结果是围手术期死亡率、血流动力学改善和术后并发症。结果患者平均年龄35.9岁。单期修复的存活率为94.1%,血压梯度从术前49.7±7.4 mmHg降至术后11.2±3.9 mmHg,血流动力学显著改善。术后并发症极少,随访期间无移植物衰竭、扭结或脑血管事件发生。1例患者出现急性肾损伤和早期死亡。长达10年的随访显示出持久的效果和良好的结果。结论单期解剖外搭桥术同时修复相关心脏缺损是治疗成人复杂CoA的一种安全有效的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simultaneous single-staged surgical management of coarctation of aorta concomitant with intra-cardiac abnormality by extra-anatomic aortic bypass grafting.

BackgroundCoarctation of the aorta (CoA) is a congenital condition that often requires intervention, especially when associated with other intracardiac abnormalities. Surgical approaches to treat complex CoA and associated defects vary, with no universally accepted standard approach. This study evaluates the outcomes of a single-stage extra-anatomic bypass from the ascending to the descending thoracic aorta, along with simultaneous correction of associated intracardiac abnormalities in adult patients.MethodsWe conducted a retrospective analysis of 17 adult patients who underwent a single-stage extra-anatomic bypass for complex CoA repair between January 2014 and December 2023. Patients were treated with an ascending to descending thoracic aorta bypass via a right-sided extra-anatomic approach, with simultaneous correction of associated cardiac defects. The primary outcomes measured were perioperative mortality, haemodynamic improvement, and post-operative complications.ResultsThe mean age of patients was 35.9 years. The single-stage repair showed a 94.1% survival rate, with significant haemodynamic improvement indicated by a reduction in blood pressure gradient from 49.7 ± 7.4 mmHg pre-operatively to 11.2 ± 3.9 mmHg post-operatively. There were minimal complications, with no evidence of graft failure, kinking, or cerebrovascular incidents during follow-up. One patient experienced acute kidney injury and early mortality. Follow-up of up to 10 years demonstrated durable results with favourable outcomes.ConclusionThe single-stage extra-anatomic bypass with simultaneous correction of associated cardiac defects is a safe and effective approach for managing complex CoA in adults.

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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
78
期刊介绍: The Asian Cardiovascular and Thoracic Annals is an international peer-reviewed journal pertaining to cardiovascular and thoracic medicine. Besides original clinical manuscripts, we welcome research reports, product reviews, reports of new techniques, and findings of special significance to Asia and the Pacific Rim. Case studies that have significant novel original observations, are instructive, include adequate methodological details and provide conclusions. Workshop proceedings, meetings and book reviews, letters to the editor, and meeting announcements are encouraged along with relevant articles from authors.
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