某三级教学医院外科肿瘤科常用药物处方模式的回顾性研究。

IF 0.9 4区 医学 Q4 ONCOLOGY
Lakshmipuram Bipin Chakravarthy, Goutham Yerrakula, Gaddam Narasimha Rao, Navakoti Kusuma Reddy, Kunkala Priyanka, Kunnur Yogeshwara Naidu, K Mounika, P Dharani Prasad, Jeevan Kumar B, K Rohith Chandra
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引用次数: 0

摘要

背景:外科肿瘤学在肿瘤治疗中起着关键作用,它将外科技术与肿瘤护理相结合。合理的药物处方对于患者的最佳治疗效果至关重要,特别是在复杂的癌症治疗环境中。目的:本研究旨在评估三级医院肿瘤外科患者的处方模式和对WHO处方指标的依从性。方法回顾性观察研究在蒂鲁帕蒂Sri Venkateshwara医学科学研究所外科肿瘤科进行,为期10个月(2023年6月至2024年3月)。共有158名年龄在18岁以上的活检确诊癌症患者被纳入研究。对处方数据进行系统评估,以确定所使用的药物类别、处方频率以及对世界卫生组织(WHO)核心处方指标的依从性。结果40 ~ 60岁患者占比最大(39.90%),女性占比最大(69.60%)。腺癌是最常见的癌症亚型(20.90%)。在抗生素中,以头孢菌素为主(92.92%),头孢呋辛是最常用的药物(31%)。89.87%的病例使用镇痛药,但阿片类药物处方仍然相对较低(5.70%)。世卫组织处方指标分析显示:每次就诊平均药物(3.15种)、仿制药处方率(75.35%)、基本药物清单依从性(73.74%)和抗生素就诊率(62.65%)。注意到与世卫组织标准的偏差,特别是在抗生素过度使用和EDL依从性方面。结论本研究确定了关键的处方趋势和与推荐做法的偏差。研究结果强调了标准化、循证处方方案的必要性,以减少外科肿瘤的不合理用药,增强患者安全,提高治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A retrospective study on the prescription pattern of commonly prescribed drugs in the Department of Surgical Oncology in a Tertiary Care Teaching Hospital.

BackgroundSurgical oncology plays a key role in cancer therapy, combining surgical techniques with oncological care. Rational drug prescribing is essential for optimal patient outcomes, particularly in complex cancer care settings.ObjectivesThis study aimed to assess prescribing patterns and adherence to WHO prescribing indicators among surgical oncology patients within a tertiary care hospital.MethodsThis retrospective observational study was executed over a ten-month period (June 2023-March 2024) in the Department of Surgical Oncology at Sri Venkateshwara Institute of Medical Sciences, Tirupati. A total of 158 biopsy-confirmed cancer patients aged above 18 years were enrolled. Prescription data were systematically evaluated to determine drug classes utilized, prescribing frequency, and adherence to World Health Organization (WHO) core prescribing indicators.ResultsPatients aged 40-60 years represented the largest proportion of the cohort (39.90%), and females accounted for the majority of cases (69.60%). Adenocarcinoma was identified as the most prevalent cancer subtype (20.90%). Among antibiotics, cephalosporins were predominantly prescribed (92.92%), with cefuroxime being the most frequently utilized agent (31%). Analgesics were administered in 89.87% of cases, although opioid prescriptions remained relatively low (5.70%). WHO prescribing indicator analysis revealed: average drugs per encounter (3.15), generic prescribing rate (75.35%), essential drug list adherence (73.74%), and antibiotic encounter rate (62.65%). Deviations from WHO standards, particularly in antibiotic overuse and EDL adherence, were noted.ConclusionThe study identifies key prescribing trends and deviations from recommended practices. The findings emphasize the need for standardized, evidence-based prescribing protocols to reduce irrational drug use, enhance patient safety, and improve treatment efficacy in surgical oncology.

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来源期刊
CiteScore
2.70
自引率
7.70%
发文量
276
期刊介绍: Journal of Oncology Pharmacy Practice is a peer-reviewed scholarly journal dedicated to educating health professionals about providing pharmaceutical care to patients with cancer. It is the official publication of the International Society for Oncology Pharmacy Practitioners (ISOPP). Publishing pertinent case reports and consensus guidelines...
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