美沙拉嗪引起的中性粒细胞减少症：一种罕见的特殊反应。

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

BMJ Case Reports Pub Date : 2025-09-14 DOI:10.1136/bcr-2025-267789

Deloshaan Subhaharan, Waled Mohsen

{"title":"美沙拉嗪引起的中性粒细胞减少症：一种罕见的特殊反应。","authors":"Deloshaan Subhaharan, Waled Mohsen","doi":"10.1136/bcr-2025-267789","DOIUrl":null,"url":null,"abstract":"Mesalazine is a 5-aminosalicylate commonly used in the treatment of ulcerative colitis. It has been very rarely associated with neutropenia. We report a woman in her 30s who developed neutropenia 2 years after starting mesalazine. She had not been started on any other medications and extensive investigation for alternative causes of neutropenia were unremarkable. Mesalazine was discontinued and her neutrophil count normalised within 2 weeks.","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 9","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mesalazine-induced neutropenia: a rare idiosyncratic reaction.\",\"authors\":\"Deloshaan Subhaharan, Waled Mohsen\",\"doi\":\"10.1136/bcr-2025-267789\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Mesalazine is a 5-aminosalicylate commonly used in the treatment of ulcerative colitis. It has been very rarely associated with neutropenia. We report a woman in her 30s who developed neutropenia 2 years after starting mesalazine. She had not been started on any other medications and extensive investigation for alternative causes of neutropenia were unremarkable. Mesalazine was discontinued and her neutrophil count normalised within 2 weeks.\",\"PeriodicalId\":9080,\"journal\":{\"name\":\"BMJ Case Reports\",\"volume\":\"18 9\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-09-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMJ Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/bcr-2025-267789\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bcr-2025-267789","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

摘要

美沙拉嗪是一种常用于治疗溃疡性结肠炎的5-氨基水杨酸盐。它很少与中性粒细胞减少症有关。我们报告一位30多岁的女性，在服用美沙拉嗪2年后出现中性粒细胞减少症。她没有开始服用任何其他药物，对中性粒细胞减少症的其他原因进行了广泛的调查，结果并不显著。停用美沙拉嗪，2周内中性粒细胞计数恢复正常。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Mesalazine-induced neutropenia: a rare idiosyncratic reaction.

Mesalazine is a 5-aminosalicylate commonly used in the treatment of ulcerative colitis. It has been very rarely associated with neutropenia. We report a woman in her 30s who developed neutropenia 2 years after starting mesalazine. She had not been started on any other medications and extensive investigation for alternative causes of neutropenia were unremarkable. Mesalazine was discontinued and her neutrophil count normalised within 2 weeks.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

BMJ Case Reports Medicine-Medicine (all)

CiteScore

1.40

自引率

0.00%

发文量

1588

期刊介绍： BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.