【先天性并指畸形临床诊治专家共识(2025年版)】。

Q4 Medicine
Hand Plastic Surgery Committee Aesthetic And Plastic Surgeon Branch Of Chinese Medical Doctor Association, Clinical Genetics Group Medical Geneticist Branch Of Chinese Medical Doctor Association, Pediatric Plastic Surgery Group Plastic Surgery Branch Of Chinese Medical Association, Assistive Devices Application Committee Chinese Rehabilitation Medicine Association, Bin Wang, Lingqian Wu
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引用次数: 0

摘要

并指畸形是最常见的先天性手/足畸形之一,其特征是相邻手指或脚趾之间不同程度的软组织和/或骨骼融合。它也可能发生在多指畸形、喜趾畸形、短指畸形或先天性关节融合。其临床表型的异质性和不完全外显性使得建立明确的诊断和治疗方案/程序具有挑战性。传统上,并指症的治疗主要依靠临床经验,很少参考前沿的遗传学研究和系统的治疗策略。为规范并指病的诊治,更新治疗方案,中国医师协会美容整形外科分会手部整形外科专业委员会、中国医师协会医学遗传学分会临床遗传学专业委员会、中国医师协会整形外科分会小儿整形外科专业委员会、和中国康复医学会辅助器具应用委员会,以及全国主要的大学和医院。这一专家共识,结合了临床和遗传研究,以及最近的国际和国内的发现,旨在作为临床医生的参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Expert consensus on the clinical diagnosis and treatment of Congenital syndactyly (2025 Edition)].

Syndactyly is one of the most common congenital malformations of the hand/foot, characterized by varying degrees of soft tissue and/or skeletal fusion between adjacent fingers or toes. It may also occur alongside polydactyly, camptodactyly, brachydactyly, or congenital joint fusion. The heterogeneity in its clinical phenotypes and incomplete penetrance makes it challenging to establish clear diagnostic and treatment protocols/procedures. Conventionally, the management of syndactyly has mainly relied on clinical experience, with limited reference to cutting-edge genetic research and systematic treatment strategies. To standardize the diagnosis and treatment of syndactyly and update the treatment protocols, a consensus has been developed by experts from the Hand Plastic Surgery Committee of the Aesthetic and Plastic Surgeon Branch of Chinese Medical Doctor Association, Clinical Genetics Group of the Medical Geneticist Branch of Chinese Medical Doctor Association, Pediatric Plastic Surgery Group of Plastic Surgery Branch of Chinese Medical Association, and Assistive Devices Application Committee of the Chinese Rehabilitation Medicine Association, and leading universities and hospitals across China. This expert consensus, incorporating both clinical and genetic research, as well as recent international and domestic findings, aims to serve as a reference for clinicians.

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来源期刊
中华医学遗传学杂志
中华医学遗传学杂志 Medicine-Medicine (all)
CiteScore
0.50
自引率
0.00%
发文量
9521
期刊介绍: Chinese Journal of Medical Genetics is a medical journal, founded in 1984, under the supervision of the China Association for Science and Technology, sponsored by the Chinese Medical Association (hosted by Sichuan University), and is now a monthly magazine, which attaches importance to academic orientation, adheres to the scientific, scholarly, advanced, and innovative, and has a certain degree of influence in the industry. Chinese Journal of Medical Genetics is a journal of Peking University, and is now included in Peking University Journal (Chinese Journal of Humanities and Social Sciences), CSCD Source Journals of Chinese Science Citation Database (with extended version), Statistical Source Journals (China Science and Technology Dissertation Outstanding Journals), Zhi.com (in Chinese), Wipu (in Chinese), Wanfang (in Chinese), CA Chemical Abstracts (U.S.), JST (Japan Science and Technology Science and Technology), and JST (Japan Science and Technology Science and Technology Research Center). ), JST (Japan Science and Technology Agency), Pж (AJ) Abstracts Journal (Russia), Copernicus Index (Poland), Cambridge Scientific Abstracts, Abstracts and Citation Database, Abstracts Magazine, Medical Abstracts, and so on.
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