小而有力：菊粉促进小肠细菌的果糖摄食

IF 20.8 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Nature metabolism Pub Date : 2025-09-15 DOI:10.1038/s42255-025-01374-y

Hallie R. Wachsmuth, Frank A. Duca

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引用次数: 0

摘要

虽然肠道微生物群有助于代谢性疾病的发展，但通过增加纤维摄入量有益地改变肠道微生物群可以改善啮齿动物和人类的代谢结果。Jung等人的一项新研究描述了一种新的机制，通过这种机制，益生元纤维菊粉可以通过在小肠微生物群中的适应性来预防和逆转肝脂肪变性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Small but mighty: inulin promotes small intestinal bacterial fructose feeding

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Small but mighty: inulin promotes small intestinal bacterial fructose feeding

Although the gut microbiome contributes to the development of metabolic disease, beneficially altering the gut microbiome via increased fibre intake improves metabolic outcomes in rodents and humans. A new study by Jung et al. describes a novel mechanism by which the prebiotic fibre, inulin, can prevent and reverse hepatic steatosis via adaptations in the small intestinal microbiome.

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来源期刊

Nature metabolism ENDOCRINOLOGY & METABOLISM-

CiteScore

27.50

自引率

2.40%

发文量

170

期刊介绍： Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.