{"title":"手部软组织手术患者口服抗凝治疗的无阿片类药物疼痛管理策略","authors":"Ellis M Berns, Thompson Zhuang, Hannah H Lee","doi":"10.1016/j.jhsa.2025.07.020","DOIUrl":null,"url":null,"abstract":"<p><p>Non-narcotic multimodal analgesia has become standard for patients undergoing soft tissue hand surgery. These regimens often include nonsteroidal anti-inflammatory drugs such as ketorolac and ibuprofen, which can elevate bleeding risks in patients on anticoagulation therapy. This review aims to (1) elucidate the physiology of coagulation in relation to nonsteroidal anti-inflammatory drugs and anticoagulants, (2) examine the current surgical literature on risks and benefits of limited-duration nonsteroidal anti-inflammatory drug use in anticoagulated patients, (3) identify viable pain management alternatives, and (4) highlight areas warranting further research in nonopioid analgesia for anticoagulated patients.</p>","PeriodicalId":54815,"journal":{"name":"Journal of Hand Surgery-American Volume","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Opioid-Free Pain Management Strategies for Patients on Oral Anticoagulation Undergoing Soft Tissue Hand Surgery.\",\"authors\":\"Ellis M Berns, Thompson Zhuang, Hannah H Lee\",\"doi\":\"10.1016/j.jhsa.2025.07.020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Non-narcotic multimodal analgesia has become standard for patients undergoing soft tissue hand surgery. These regimens often include nonsteroidal anti-inflammatory drugs such as ketorolac and ibuprofen, which can elevate bleeding risks in patients on anticoagulation therapy. This review aims to (1) elucidate the physiology of coagulation in relation to nonsteroidal anti-inflammatory drugs and anticoagulants, (2) examine the current surgical literature on risks and benefits of limited-duration nonsteroidal anti-inflammatory drug use in anticoagulated patients, (3) identify viable pain management alternatives, and (4) highlight areas warranting further research in nonopioid analgesia for anticoagulated patients.</p>\",\"PeriodicalId\":54815,\"journal\":{\"name\":\"Journal of Hand Surgery-American Volume\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hand Surgery-American Volume\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jhsa.2025.07.020\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hand Surgery-American Volume","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jhsa.2025.07.020","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Opioid-Free Pain Management Strategies for Patients on Oral Anticoagulation Undergoing Soft Tissue Hand Surgery.
Non-narcotic multimodal analgesia has become standard for patients undergoing soft tissue hand surgery. These regimens often include nonsteroidal anti-inflammatory drugs such as ketorolac and ibuprofen, which can elevate bleeding risks in patients on anticoagulation therapy. This review aims to (1) elucidate the physiology of coagulation in relation to nonsteroidal anti-inflammatory drugs and anticoagulants, (2) examine the current surgical literature on risks and benefits of limited-duration nonsteroidal anti-inflammatory drug use in anticoagulated patients, (3) identify viable pain management alternatives, and (4) highlight areas warranting further research in nonopioid analgesia for anticoagulated patients.
期刊介绍:
The Journal of Hand Surgery publishes original, peer-reviewed articles related to the pathophysiology, diagnosis, and treatment of diseases and conditions of the upper extremity; these include both clinical and basic science studies, along with case reports. Special features include Review Articles (including Current Concepts and The Hand Surgery Landscape), Reviews of Books and Media, and Letters to the Editor.