髂内干预对腹主动脉瘤破裂血管内修复中死亡率和肠道缺血的影响。

IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE
Vascular Pub Date : 2025-09-12 DOI:10.1177/17085381251379846
Jose Oyama Leite, Sung H Yang, Amit Jain, Joseph S Giglia, Jiarong Ouyang, Xuan Cao
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引用次数: 0

摘要

目的腹主动脉瘤破裂(RAAA)是一种危及生命的血管急症,尽管手术和血管内技术已取得进展,但其死亡率很高。本研究评估髂内动脉干预对RAAA患者行血管内动脉瘤修复(EVAR)的短期(30天)和长期(6564天)死亡率和肠缺血的影响。方法采用血管质量倡议(VQI)数据库,对2004 - 2022年间4274例因RAAA接受急诊EVAR的患者进行回顾性分析。根据髂内动脉干预的类型将患者分为四组:不干预、至少一条髂内动脉血运重建、两条髂内动脉闭塞和一条髂内动脉闭塞。使用卡方检验比较死亡率和肠道缺血结局,并使用logistic回归模型确定显著预测因子。结果两组间短期死亡率(p = .5638)和长期死亡率(p = .5776)差异均无统计学意义。第3组(双髂内动脉闭塞)肠缺血发生率最高(11.36%),30天死亡率最高(31.11%),但差异无统计学意义。肠缺血使长期死亡率增加2.82倍(p < 0.001)。高龄和术前肌酐水平是死亡率的强预测因子:每增加一岁,死亡几率增加7% (p < 0.0001), COPD的存在使长期死亡率增加51% (p < 0.001)。延长手术时间和失血也与长期死亡和肠缺血的高风险相关。结论髂内干预类型对短期和长期死亡率无显著影响,但减少术中延长手术时间和失血过多等因素对提高短期生存率和降低肠缺血风险至关重要。管理慢性阻塞性肺病(COPD)等慢性疾病和优化肾功能对于改善长期预后至关重要,特别是对高龄和全身性疾病的高风险患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of internal iliac interventions on mortality and intestinal ischemia in ruptured abdominal aortic aneurysm endovascular repair.

ObjectivesRuptured abdominal aortic aneurysm (RAAA) is a life-threatening vascular emergency with high mortality rate despite advances in surgical and endovascular techniques. This study evaluates the impact of internal iliac artery interventions on short-term (30-day) and long-term (up to 6564 days) mortality and intestinal ischemia in patients undergoing endovascular aneurysm repair (EVAR) for RAAA.MethodsA retrospective analysis of 4274 patients who underwent emergent EVAR for RAAA between 2004 and 2022 was conducted using the Vascular Quality Initiative (VQI) database. Patients were stratified into four groups based on the type of internal iliac intervention: no intervention, revascularization of at least one internal iliac artery, occlusion of both internal iliac arteries, and occlusion of one internal iliac artery. Mortality and intestinal ischemic outcomes were compared using chi-square tests, and logistic regression models were used to identify significant predictors.ResultsNo statistically significant differences in short-term (p = .5638) or long-term mortality (p = .5776) were observed between groups. Group 3 (occlusion of both internal iliac arteries) had the highest rates of intestinal ischemia (11.36%) and 30-day mortality (31.11%), though these differences were not statistically significant. Intestinal ischemia increased the odds of long-term mortality by 2.82 times (p < .001). Advanced age and preoperative creatinine levels were strong predictors of mortality: each additional year of age increased the odds of death by 7% (p < .0001), and the presence of COPD raised the odds of long-term mortality by 51% (p < .001). Prolonged procedure time and blood loss were also associated with higher risks of both long-term mortality and intestinal ischemia.ConclusionsThe type of internal iliac intervention did not significantly affect short-term or long-term mortality, but mitigating intraoperative factors such as prolonged procedure time and excessive blood loss is critical for improving short-term survival and reducing the risk of intestinal ischemia. Managing chronic conditions like COPD and optimizing renal function are essential to improving long-term outcomes, especially in high-risk patients with advanced age and systemic disease.

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来源期刊
Vascular
Vascular 医学-外周血管病
CiteScore
2.30
自引率
9.10%
发文量
196
审稿时长
6-12 weeks
期刊介绍: Vascular provides readers with new and unusual up-to-date articles and case reports focusing on vascular and endovascular topics. It is a highly international forum for the discussion and debate of all aspects of this distinct surgical specialty. It also features opinion pieces, literature reviews and controversial issues presented from various points of view.
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