代谢功能障碍相关脂肪性肝炎和心脏代谢疾病的多学科治疗综述,以加拿大为重点

IF 5.7 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
James Kim, Paolo Raggi, Anne-Marie Carreau, Sean Wharton, Alice Y Y Cheng, Mark G Swain
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引用次数: 0

摘要

心脏代谢疾病(CMD)与代谢功能障碍相关脂肪性肝炎(MASH)的风险增加相关。大多数患者与2型糖尿病和肥胖有关。最佳的疾病管理需要初级保健医生和来自不同医学领域的专家之间有效的多学科合作;然而,非肝脏专家对MASH的风险、与CMD的关联、诊断、并发症和管理策略的认识较低。在加拿大,诊断检测的可及性各不相同,而且直到最近还缺乏全国性的MASH指南,这也是有效管理疾病的障碍。需要持续的跨学科教育和广泛的系统变革,以确保及时识别患者并建立全面的患者护理途径,从而开始解决MASH和相关的CMD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A review of multidisciplinary care in metabolic dysfunction-associated steatohepatitis and cardiometabolic disease, with a focus on Canada.

Cardiometabolic disease (CMD) is associated with an increased risk of metabolic dysfunction-associated steatohepatitis (MASH). Most patients develop MASH in association with type 2 diabetes and obesity. Optimal disease management requires effective multidisciplinary collaboration between primary care physicians and specialists from different medical fields; however, awareness of the risks, association with CMD, diagnosis, complications, and management strategies of MASH is low among non-liver specialists. In Canada, variable access to diagnostic testing and, until recently, the lack of national MASH guidelines, are also barriers to effective disease management. Ongoing cross-disciplinary education and wide systemic changes are required to ensure timely patient identification and the establishment of holistic patient care pathways that can begin to address MASH and associated CMD.

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来源期刊
Diabetes, Obesity & Metabolism
Diabetes, Obesity & Metabolism 医学-内分泌学与代谢
CiteScore
10.90
自引率
6.90%
发文量
319
审稿时长
3-8 weeks
期刊介绍: Diabetes, Obesity and Metabolism is primarily a journal of clinical and experimental pharmacology and therapeutics covering the interrelated areas of diabetes, obesity and metabolism. The journal prioritises high-quality original research that reports on the effects of new or existing therapies, including dietary, exercise and lifestyle (non-pharmacological) interventions, in any aspect of metabolic and endocrine disease, either in humans or animal and cellular systems. ‘Metabolism’ may relate to lipids, bone and drug metabolism, or broader aspects of endocrine dysfunction. Preclinical pharmacology, pharmacokinetic studies, meta-analyses and those addressing drug safety and tolerability are also highly suitable for publication in this journal. Original research may be published as a main paper or as a research letter.
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