James Kim, Paolo Raggi, Anne-Marie Carreau, Sean Wharton, Alice Y Y Cheng, Mark G Swain
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A review of multidisciplinary care in metabolic dysfunction-associated steatohepatitis and cardiometabolic disease, with a focus on Canada.
Cardiometabolic disease (CMD) is associated with an increased risk of metabolic dysfunction-associated steatohepatitis (MASH). Most patients develop MASH in association with type 2 diabetes and obesity. Optimal disease management requires effective multidisciplinary collaboration between primary care physicians and specialists from different medical fields; however, awareness of the risks, association with CMD, diagnosis, complications, and management strategies of MASH is low among non-liver specialists. In Canada, variable access to diagnostic testing and, until recently, the lack of national MASH guidelines, are also barriers to effective disease management. Ongoing cross-disciplinary education and wide systemic changes are required to ensure timely patient identification and the establishment of holistic patient care pathways that can begin to address MASH and associated CMD.
期刊介绍:
Diabetes, Obesity and Metabolism is primarily a journal of clinical and experimental pharmacology and therapeutics covering the interrelated areas of diabetes, obesity and metabolism. The journal prioritises high-quality original research that reports on the effects of new or existing therapies, including dietary, exercise and lifestyle (non-pharmacological) interventions, in any aspect of metabolic and endocrine disease, either in humans or animal and cellular systems. ‘Metabolism’ may relate to lipids, bone and drug metabolism, or broader aspects of endocrine dysfunction. Preclinical pharmacology, pharmacokinetic studies, meta-analyses and those addressing drug safety and tolerability are also highly suitable for publication in this journal. Original research may be published as a main paper or as a research letter.