每个胰腺癌患者都是姑息治疗患者吗?

4区 医学 Q2 Nursing
Nishitha Reddy, Khaldoun Almhanna, Jacob Ramos, Dana Guyer
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引用次数: 0

摘要

胰腺癌是一种侵袭性疾病,经常出现在没有治疗选择的晚期。该疾病的特点通常是进展迅速,对标准治疗的反应有限或短暂,并对患者的生活质量产生深远影响。尽管靶向治疗和免疫治疗取得了进展,但大多数晚期或高级别疾病患者的5年生存率低于10%,治疗结果仍然难以捉摸。治疗目标必须从延长生存期发展到包括减轻痛苦、优化功能和维护尊严。在这方面,姑息治疗发挥着至关重要和不可或缺的作用。即使最初表现为可切除疾病的患者在未来也有很高的复发风险。胰腺癌有很高的症状负担,包括疼痛、营养不良、吸收不良、黄疸、疲劳和抑郁。鉴于整体预后不良,早期整合姑息治疗对于解决患者的身体、情感和精神需求,并在复杂的决策中为患者和家属提供指导至关重要。事实一再证明,早期姑息治疗可以改善症状控制,减少住院治疗,甚至可以提高生存率。姑息治疗应与积极治疗同时提供,然后才能成为晚期疾病患者的主要护理重点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is every pancreatic cancer patient a palliative care patient?

ancreatic cancer is an aggressive disease and often presents at an advanced stage with no curative options. The disease is often characterized by rapid progression, limited or short-lived responsiveness to standard therapies, and a profound impact on patients' quality of life. Despite advances in targeted therapies and immunotherapy, curative outcomes remain elusive for the majority of patients with advanced or high-grade disease with a 5-year survival rate of less than 10%. Treatment goals must evolve beyond prolonging survival to include alleviating suffering, optimizing function, and preserving dignity. This is where palliative care assumes a vital and indispensable role. Even patients who initially present with resectable disease are at a high risk of recurrence in the future. Pancreatic cancer carries a high symptomatic burden from pain, poor nutrition, malabsorption, jaundice, fatigue as well as depression. Given the overall poor prognosis, early integration of palliative care is essential to address the physical, emotional and spiritual needs of patients and provide patients and families guidance in complex decision-making. Early palliative care involvement has proven time and time again to improve symptoms control, reduce hospitalization and may even improve survival. Palliative care should be provided concurrently with active treatment before becoming the main focus of care for patients with advanced stages of disease.

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来源期刊
Annals of palliative medicine
Annals of palliative medicine Medicine-Anesthesiology and Pain Medicine
自引率
0.00%
发文量
231
期刊介绍: Annals of Palliative Medicine (Ann Palliat Med; Print ISSN 2224-5820; Online ISSN 2224-5839) is an open access, international, peer-reviewed journal published quarterly with both online and printed copies since 2012. The aim of the journal is to provide up-to-date and cutting-edge information and professional support for health care providers in palliative medicine disciplines to improve the quality of life for patients and their families and caregivers.
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