Mengqing Su , Xiaopeng Yu , Qianyu Wu , Wenhui Qin , Guotao Quan , Yanyan Liu , Wenying Wang , Yang Chen , Xiaochun Lai , Xu Ji
{"title":"基于边缘计算的FPGA光子计数CT实时材料分解系统","authors":"Mengqing Su , Xiaopeng Yu , Qianyu Wu , Wenhui Qin , Guotao Quan , Yanyan Liu , Wenying Wang , Yang Chen , Xiaochun Lai , Xu Ji","doi":"10.1016/j.cmpb.2025.109040","DOIUrl":null,"url":null,"abstract":"<div><h3>Background:</h3><div>Photon counting computed tomography (PCCT) has emerged as a potential technology that is revolutionizing clinical CT imaging. Using photon counting detectors (PCDs), the PCCT counts each X-ray event and measures the corresponding energy above the noise floor with significantly higher spatial resolution. However, the multiple-energy-bin setting and much smaller pixels increase the raw data size of PCCT by 20–100 times compared to traditional CT. The current bandwidth of the slip ring struggles to handle such a large volume of data.</div></div><div><h3>Methods:</h3><div>To address the challenge above, we propose an innovative edge computing-based PCCT data processing flow and implement a fast material decomposition program directly on an FPGA system. Our approach eliminates the need to transfer raw data from the CT gantry for later offline processing. Instead, we develop real-time material decomposition and embed the algorithm into an FPGA, which is typically integrated in current PCDs.</div></div><div><h3>Results:</h3><div>Visual and quantitative results on the real phantom dataset have shown that the proposed system can efficiently generate ring-artifact-free and accurate material decomposition results, while also reducing the data volume.</div></div><div><h3>Conclusion:</h3><div>Our proposed system effectively migrates the offline material decomposition processing to the detector blade, thereby fully leveraging the FPGA resources available within the CT gantry to rapidly obtain material decomposition results. Compared to the traditional process flow, our approach offers significantly faster speed and higher throughput, while maintaining the same level of precision as offline processing.</div></div>","PeriodicalId":10624,"journal":{"name":"Computer methods and programs in biomedicine","volume":"272 ","pages":"Article 109040"},"PeriodicalIF":4.8000,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Edge computing-based FPGA real-time material decomposition system for photon counting CT\",\"authors\":\"Mengqing Su , Xiaopeng Yu , Qianyu Wu , Wenhui Qin , Guotao Quan , Yanyan Liu , Wenying Wang , Yang Chen , Xiaochun Lai , Xu Ji\",\"doi\":\"10.1016/j.cmpb.2025.109040\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background:</h3><div>Photon counting computed tomography (PCCT) has emerged as a potential technology that is revolutionizing clinical CT imaging. Using photon counting detectors (PCDs), the PCCT counts each X-ray event and measures the corresponding energy above the noise floor with significantly higher spatial resolution. However, the multiple-energy-bin setting and much smaller pixels increase the raw data size of PCCT by 20–100 times compared to traditional CT. The current bandwidth of the slip ring struggles to handle such a large volume of data.</div></div><div><h3>Methods:</h3><div>To address the challenge above, we propose an innovative edge computing-based PCCT data processing flow and implement a fast material decomposition program directly on an FPGA system. Our approach eliminates the need to transfer raw data from the CT gantry for later offline processing. Instead, we develop real-time material decomposition and embed the algorithm into an FPGA, which is typically integrated in current PCDs.</div></div><div><h3>Results:</h3><div>Visual and quantitative results on the real phantom dataset have shown that the proposed system can efficiently generate ring-artifact-free and accurate material decomposition results, while also reducing the data volume.</div></div><div><h3>Conclusion:</h3><div>Our proposed system effectively migrates the offline material decomposition processing to the detector blade, thereby fully leveraging the FPGA resources available within the CT gantry to rapidly obtain material decomposition results. Compared to the traditional process flow, our approach offers significantly faster speed and higher throughput, while maintaining the same level of precision as offline processing.</div></div>\",\"PeriodicalId\":10624,\"journal\":{\"name\":\"Computer methods and programs in biomedicine\",\"volume\":\"272 \",\"pages\":\"Article 109040\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2025-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computer methods and programs in biomedicine\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0169260725004572\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer methods and programs in biomedicine","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0169260725004572","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
Edge computing-based FPGA real-time material decomposition system for photon counting CT
Background:
Photon counting computed tomography (PCCT) has emerged as a potential technology that is revolutionizing clinical CT imaging. Using photon counting detectors (PCDs), the PCCT counts each X-ray event and measures the corresponding energy above the noise floor with significantly higher spatial resolution. However, the multiple-energy-bin setting and much smaller pixels increase the raw data size of PCCT by 20–100 times compared to traditional CT. The current bandwidth of the slip ring struggles to handle such a large volume of data.
Methods:
To address the challenge above, we propose an innovative edge computing-based PCCT data processing flow and implement a fast material decomposition program directly on an FPGA system. Our approach eliminates the need to transfer raw data from the CT gantry for later offline processing. Instead, we develop real-time material decomposition and embed the algorithm into an FPGA, which is typically integrated in current PCDs.
Results:
Visual and quantitative results on the real phantom dataset have shown that the proposed system can efficiently generate ring-artifact-free and accurate material decomposition results, while also reducing the data volume.
Conclusion:
Our proposed system effectively migrates the offline material decomposition processing to the detector blade, thereby fully leveraging the FPGA resources available within the CT gantry to rapidly obtain material decomposition results. Compared to the traditional process flow, our approach offers significantly faster speed and higher throughput, while maintaining the same level of precision as offline processing.
期刊介绍:
To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine.
Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.