{"title":"成人重型外伤合并孤立性胸腹外伤合并失血性休克的复苏性血管内球囊闭塞术(REBOA)疗效观察","authors":"Sanjan Kumar B.S , Philip Lee B.S , Ariel Hus B.S , Ruth Zagales B.S , Cameron Nishida B.S , Deepa Elangovan B.S , Kathleen Schuemann MD, FACS , Adel Elkbuli MD, MPH, MBA","doi":"10.1016/j.ajem.2025.08.068","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>There is conflicting literature regarding mortality outcomes associated with REBOA usage in patients with severe thoracic or abdominal trauma. Our study aims to assess the benefits and negative implications of REBOA use in adult trauma patients in hemorrhagic shock with severe thoracic or abdominal injuries.</div></div><div><h3>Methods</h3><div>This retrospective cohort analysis utilized the American College of Surgeons Trauma Quality Improvement Program Participant Use File (ACS-TQIP-PUF) database from 2017 to 2023 to evaluate adult patients with severe isolated thoracic or abdominal trauma undergoing REBOA placement. Patients were stratified by REBOA zone, type of injury, and trauma center level. Primary outcomes included Emergency Department (ED) and 24-h mortality. Secondary outcomes included time to hemorrhage control, transfusion volumes, and complications.</div></div><div><h3>Results</h3><div>In severely injured adult trauma patients with thoracic or abdominal injuries, REBOA was significantly associated with increased mortality (aOR: 15.456, 95 % CI: 3.340–71.516, <em>p</em> < 0.001), 4-h transfusion requirements (β = 3177.081, 95 % CI: 59.315–6294.848, <em>p</em> = 0.046), and 24-h transfusion requirements (β = 2750.609, 95 % CI: 704.078–4797.141, <em>p</em> = 0.008) in both blunt and penetrating injuries. Patients who underwent REBOA at level II trauma centers had greater odds of 24-h mortality. No significant differences were observed in time to hemorrhage control or complication rates.</div></div><div><h3>Conclusion</h3><div>REBOA use in adult trauma patients with severe thoracic or abdominal trauma consistently led to increased mortality and blood transfusion requirements even when outcomes were stratified by REBOA zone placement and trauma center level. REBOA use should be cautiously considered on a case-by-case basis in severely injured patients.</div></div>","PeriodicalId":55536,"journal":{"name":"American Journal of Emergency Medicine","volume":"98 ","pages":"Pages 245-255"},"PeriodicalIF":2.2000,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Outcomes of resuscitative endovascular balloon occlusion of the aorta (REBOA) in severely injured adult trauma patients with isolated thoracic or abdominal trauma in Hemorrhagic shock\",\"authors\":\"Sanjan Kumar B.S , Philip Lee B.S , Ariel Hus B.S , Ruth Zagales B.S , Cameron Nishida B.S , Deepa Elangovan B.S , Kathleen Schuemann MD, FACS , Adel Elkbuli MD, MPH, MBA\",\"doi\":\"10.1016/j.ajem.2025.08.068\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>There is conflicting literature regarding mortality outcomes associated with REBOA usage in patients with severe thoracic or abdominal trauma. Our study aims to assess the benefits and negative implications of REBOA use in adult trauma patients in hemorrhagic shock with severe thoracic or abdominal injuries.</div></div><div><h3>Methods</h3><div>This retrospective cohort analysis utilized the American College of Surgeons Trauma Quality Improvement Program Participant Use File (ACS-TQIP-PUF) database from 2017 to 2023 to evaluate adult patients with severe isolated thoracic or abdominal trauma undergoing REBOA placement. Patients were stratified by REBOA zone, type of injury, and trauma center level. Primary outcomes included Emergency Department (ED) and 24-h mortality. Secondary outcomes included time to hemorrhage control, transfusion volumes, and complications.</div></div><div><h3>Results</h3><div>In severely injured adult trauma patients with thoracic or abdominal injuries, REBOA was significantly associated with increased mortality (aOR: 15.456, 95 % CI: 3.340–71.516, <em>p</em> < 0.001), 4-h transfusion requirements (β = 3177.081, 95 % CI: 59.315–6294.848, <em>p</em> = 0.046), and 24-h transfusion requirements (β = 2750.609, 95 % CI: 704.078–4797.141, <em>p</em> = 0.008) in both blunt and penetrating injuries. Patients who underwent REBOA at level II trauma centers had greater odds of 24-h mortality. No significant differences were observed in time to hemorrhage control or complication rates.</div></div><div><h3>Conclusion</h3><div>REBOA use in adult trauma patients with severe thoracic or abdominal trauma consistently led to increased mortality and blood transfusion requirements even when outcomes were stratified by REBOA zone placement and trauma center level. REBOA use should be cautiously considered on a case-by-case basis in severely injured patients.</div></div>\",\"PeriodicalId\":55536,\"journal\":{\"name\":\"American Journal of Emergency Medicine\",\"volume\":\"98 \",\"pages\":\"Pages 245-255\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Emergency Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0735675725006084\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Emergency Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0735675725006084","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
Outcomes of resuscitative endovascular balloon occlusion of the aorta (REBOA) in severely injured adult trauma patients with isolated thoracic or abdominal trauma in Hemorrhagic shock
Background
There is conflicting literature regarding mortality outcomes associated with REBOA usage in patients with severe thoracic or abdominal trauma. Our study aims to assess the benefits and negative implications of REBOA use in adult trauma patients in hemorrhagic shock with severe thoracic or abdominal injuries.
Methods
This retrospective cohort analysis utilized the American College of Surgeons Trauma Quality Improvement Program Participant Use File (ACS-TQIP-PUF) database from 2017 to 2023 to evaluate adult patients with severe isolated thoracic or abdominal trauma undergoing REBOA placement. Patients were stratified by REBOA zone, type of injury, and trauma center level. Primary outcomes included Emergency Department (ED) and 24-h mortality. Secondary outcomes included time to hemorrhage control, transfusion volumes, and complications.
Results
In severely injured adult trauma patients with thoracic or abdominal injuries, REBOA was significantly associated with increased mortality (aOR: 15.456, 95 % CI: 3.340–71.516, p < 0.001), 4-h transfusion requirements (β = 3177.081, 95 % CI: 59.315–6294.848, p = 0.046), and 24-h transfusion requirements (β = 2750.609, 95 % CI: 704.078–4797.141, p = 0.008) in both blunt and penetrating injuries. Patients who underwent REBOA at level II trauma centers had greater odds of 24-h mortality. No significant differences were observed in time to hemorrhage control or complication rates.
Conclusion
REBOA use in adult trauma patients with severe thoracic or abdominal trauma consistently led to increased mortality and blood transfusion requirements even when outcomes were stratified by REBOA zone placement and trauma center level. REBOA use should be cautiously considered on a case-by-case basis in severely injured patients.
期刊介绍:
A distinctive blend of practicality and scholarliness makes the American Journal of Emergency Medicine a key source for information on emergency medical care. Covering all activities concerned with emergency medicine, it is the journal to turn to for information to help increase the ability to understand, recognize and treat emergency conditions. Issues contain clinical articles, case reports, review articles, editorials, international notes, book reviews and more.