密码生物学中扩展机制的几个模型。

IF 1.9 4区 生物学 Q2 BIOLOGY
Lukáš Zámečník, Barbora Jurková
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引用次数: 0

摘要

Barbieri的语义生物学(最初Barbieri 1985)通过一个新的理论实体:代码,提供了标准生物学本体的扩展。Barbieri在生物学中的语义转向的一个具体特征是使用生命系统的机械解释。这种方法允许将意义作为生物学的“新观察”。Barbieri将意义与符码的关系表述为:“[…]意义是一个实体通过代码与另一个实体相关联。”(Barbieri 2015,26)。Barbieri将意义的机制模型称为“扩展机制”。这项工作是对之前发表的一篇论文的后续研究,在那篇论文中,我们得出结论,冯·诺伊曼探测器(以及图灵机)可以作为“Barbieri扩展机制的最小充分模型”(jurkova和Zámečník 2023a)。在此基础上,我们把诺伯特·维纳提出的自我繁殖的概念联系起来。首先,为了进一步探索“扩展机制”,同时也试图强调自我繁殖作为生物过程模型的重要性。我们想强调冯·诺伊曼和维纳合作的程度,以及他们对自我繁殖的理解和概念的分歧。与冯·诺伊曼不同,维纳强调这样的机器是“完成某些明确目的的机构”(Wiener 2019/1948, 245),自我传播“是创造具有相同功能的复制品”(Wiener 2019/1948, 245)。我们认为,当维纳从使机器能够自我传播的“操作程序”的角度看待机器时,他隐含地指的是代码在Barbieri扩展机制中的主题化作用(Wiener 2019/1948, 249)。我们不仅要关注经典的科学出版物,还要分析冯·诺伊曼和维纳之间的私人通信,他们在通信中讨论了这个问题,以及它如何改变我们对自我复制机器的看法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On some models of extended mechanism in code biology
Barbieri's semantic biology (originally Barbieri, 1985) provides an extension of the standard biological ontology, through a new theoretical entity: the code. A specific feature of Barbieri's semantic turn in biology is the use of mechanistic explanations of living systems. This approach allows to work with meaning as the ‘new observable’ of biology. The relationship between meaning and code is expressed by Barbieri as follows: “[ …] meaning is an entity which is related to another entity by a code.” (Barbieri, 2015, 26). Barbieri refers to the mechanistic model of meaning as an ‘extended mechanism’.
This work is a follow-up to a previously published paper in which we concluded that the von Neumann probe (and thus the Turing machine) can serve as a “minimal sufficient model of Barbieri's extended mechanism” (Jurková and Zámečník, 2023a). We now build on this by connecting the concept of self-reproduction as conceived by Norbert Wiener. Firstly, in order to further explore the ‘extended mechanism’, but also in an attempt to highlight the importance of self-reproduction as a model of biological processes. We want to highlight the extent to which von Neumann and Wiener collaborated, but also where their understanding and conception of self-reproduction diverge.
Wiener, unlike von Neumann, emphasizes that such a machine is “an agency for accomplishing certain definite purposes” (Wiener, 2019/1948, 245) and self-propagation “is the creation of a replica capable of the same functions” (Wiener, 2019/1948, 245). We suggest that when Wiener views the machine in terms of an ‘operative procedure’ that enables machine self-propagation, he is implicitly referring to the role of code as thematized in Barbieri's extended mechanism (Wiener, 2019/1948, 249). We want to focus not only on classical scientific publications, but also to analyse the personal correspondence between von Neumann and Wiener in which they discussed the issue and how it can change the way we perceive self-reproducing machine.
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来源期刊
Biosystems
Biosystems 生物-生物学
CiteScore
3.70
自引率
18.80%
发文量
129
审稿时长
34 days
期刊介绍: BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.
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