Josefsson等人的信:“在髋关节置换术中,与锥形抛光柄相比,骨水泥解剖柄可降低假体周围骨折率:一项为期6年的前瞻性观察队列研究”

IF 2.7 Q2 ORTHOPEDICS
Peter Wahl, Emanuel Gautier
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Additional design features of the collarless polished taper (CPT) stem (Zimmer Biomet, Zug, Switzerland)—such as its length, its shoulder profile requiring sufficient lateral broaching, and the integrated cement mantle of 2 mm incorporated into the broaches of Exeter designs—may have contributed to technical difficulties, particularly in patients with narrow medullary canals. Furthermore, the higher dislocation rates in the force-closed group might reinforce concerns regarding a suboptimal technique. This interpretation is further supported by the uncommonly high rate of periprosthetic joint infection (PJI) in this study, as the global rate of PJI was 2.6%, and particularly high in the force-closed group with 3.6%, compared to a commonly accepted 1% rate for THA [<span>2, 3</span>]. 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引用次数: 0

摘要

我们饶有兴趣地阅读了Josefsson等人最近发表在《实验骨科杂志》上的一篇文章,题为“在髋关节置换术中,骨水泥解剖与锥形抛光柄相比降低假体周围骨折率:一项为期6年的前瞻性观察队列研究”。长期以来,人们一直认为将全髋关节置换术中的固定物仅仅分类为“骨水泥”或“未骨水泥”过于简单,不能公正地对待基本的结果决定因素,我们很高兴看到作者使用力封闭(或锥形滑移)或形状封闭的概念来解决骨水泥柄之间的差异。尽管这些区别具有临床意义,但它们往往被低估了。值得注意的是,已观察到不同固定原则之间的复习率存在差异,特别是与混合概念(如法国悖论技术[7])相关的复习风险更高且逐渐增加。在纯概念中,在股骨近端假体周围骨折(PPF)的风险方面,形状封闭设计比力封闭设计表现得更好,本研究[4]和最近发表的文献荟萃分析系统综述[6]都证实了这一点。然而,我们希望提请注意图1中一个可能的错误,其中图例似乎被颠倒了。考虑到这个数字在传达研究的关键发现中的重要性,我们建议发布一个更正:橙色曲线应对应于抛光的锥形茎,蓝色曲线对应于解剖茎。除此之外,我们认为结果值得进行更细致的讨论,特别是考虑到分析中未解决的潜在混杂因素。在全髋关节置换术后,力闭组发生PPF的时间模式不典型,更接近于术后早期未胶结的茎[1]。这可能反映了术中问题,而不是骨水泥概念的固有缺陷。骨折类型的分布(见原始出版物的图2)可能同样表明手术技术问题,例如过度咄咄逼人的拉削。无颈圈抛光锥度(CPT)柄(Zimmer Biomet, Zug, Switzerland)的其他设计特征——例如其长度、肩部轮廓需要足够的横向拉削,以及Exeter设计的拉削中包含2mm的集成水泥套——可能会导致技术困难,特别是在髓管狭窄的患者中。此外,力封闭组中较高的脱位率可能会加强对次优技术的关注。本研究中假体周围关节感染(PJI)的发生率异常高,这进一步支持了这一解释,全球PJI发生率为2.6%,与普遍接受的THA发生率1%相比,强制关闭组的PJI发生率特别高,为3.6%[2,3]。排除早期骨折——那些最可能与术中问题相关的骨折——翻修率之间的差异缩小并变得不再显著,因为置信区间在很大程度上重叠,即使强行闭合组的增加率似乎更高(图2)。最后,值得注意的是,作者在强制封闭组中使用的CPT系统比它进化而来的埃克塞特系统具有更高的修订率。这很可能是由于该阀杆使用钴铬合金而不是不锈钢,后者在修正风险方面的风险比为6.7。虽然我们赞扬作者的宝贵贡献,但我们要警告不要将研究结果推广到所有力闭系统。观察到的结果可能是特定于CPT茎,甚至可能是特定于局部手术因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Letter to the Editor Josefsson et al. ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’

Letter to the Editor Josefsson et al. ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’

Letter to the Editor Josefsson et al. ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’

Letter to the Editor Josefsson et al. ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’

Letter to the Editor Josefsson et al. ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’

We read with great interest the recent publication in the Journal of Experimental Orthopaedics by Josefsson et al., entitled ‘Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study’ [4]. As long-standing proponents of the view that classifying fixation in total hip arthroplasty merely as ‘cemented’ or ‘uncemented’ is overly simplistic, not doing justice to essential outcome determinants, we were pleased to see the authors address differences between cemented stems using either a force-closed (or taper-slip) or a shape-closed concept. These distinctions are often underappreciated, despite their clinical relevance. Notably, variation in revision rates between fixation principles have been observed, particularly higher and progressively increasing revision risks associated with mixed concepts such as the French paradox technique [7]. Among the pure concepts, shape-closed designs perform much better than force-closed designs regarding the risk of periprosthetic fractures (PPF) of the proximal femur, as corroborated by both the present study [4] and a recently published systematic review of the literature with meta-analysis [6].

However, we would like to draw attention to a likely error in Figure 1, where the legend appears to have been inverted. Given the importance of this figure in conveying the study's key findings, we suggest issuing a corrigendum: the orange curve should correspond to polished tapered stems, and the blue curve to anatomic stems.

Beyond this, we believe the results merit a more nuanced discussion, particularly in light of potential confounding factors not addressed in the analysis. The temporal pattern of occurrence of PPF after THA in the force-closed stem group appears atypical, resembling more closely the early postoperative profile of uncemented stems [1]. This may reflect intraoperative issues rather than inherent shortcomings of the cementation concept. The distribution of fracture types (illustrated in Figure 2 of the original publication) might similarly indicate surgical technique issues, such as overly aggressive broaching. Additional design features of the collarless polished taper (CPT) stem (Zimmer Biomet, Zug, Switzerland)—such as its length, its shoulder profile requiring sufficient lateral broaching, and the integrated cement mantle of 2 mm incorporated into the broaches of Exeter designs—may have contributed to technical difficulties, particularly in patients with narrow medullary canals. Furthermore, the higher dislocation rates in the force-closed group might reinforce concerns regarding a suboptimal technique. This interpretation is further supported by the uncommonly high rate of periprosthetic joint infection (PJI) in this study, as the global rate of PJI was 2.6%, and particularly high in the force-closed group with 3.6%, compared to a commonly accepted 1% rate for THA [2, 3]. Excluding early fractures—those most plausibly linked to intraoperative issues - the difference between the revision rates narrows and becomes no more significant, as the confidence intervals largely overlap, even if the increase rate seems higher in the force-closed group (Figure 2).

Finally, it is worth noting that the CPT stem the authors used in the force-closed group is well-known to have higher revision rates than the Exeter stem it evolved from. This may well be attributable to the use of a cobalt-chromium alloy for this stem rather than stainless steel, which has been associated with a hazard ratio of 6.7 regarding revision risks [5].

While we commend the authors for their valuable contribution, we would caution against generalising the findings to all force-closed stems. The observed outcomes may be specific to the CPT stem and potentially even be specific to local surgical factors.

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来源期刊
Journal of Experimental Orthopaedics
Journal of Experimental Orthopaedics Medicine-Orthopedics and Sports Medicine
CiteScore
3.20
自引率
5.60%
发文量
114
审稿时长
13 weeks
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