N-N偶联一锅直接电化学合成2h -吲哚

IF 2 3区化学 Q2 CHEMISTRY, ORGANIC

Journal of Heterocyclic Chemistry Pub Date : 2025-07-11 DOI:10.1002/jhet.70018

Abhishek Upadhyay, Sumit Moulekhi, Vinay Kumar Singh, Manjula Singh, Manoj Kumar Patel, G. K. Mishra, L. P. Gupta, N. K. Awasthi, R. K. P. Singh

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引用次数: 0

摘要

本文介绍了在乙氧基溶剂中，利用2-叠氮苯甲醛和苯胺的相互作用，通过N-N键偶联合成2h -吲哚唑衍生物的环保方法。以六氟磷酸四丁基铵（Bu4NPF6）为支撑电解质，在室温下的未分裂电池中进行恒流电合成。该协议的诱人品质包括清洁合成，使用电力而不是化学试剂，以及原子经济性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A Convenient Electrochemical One-Pot Direct Synthesis of 2H-Indazoles via N–N Coupling

This article describes an environmentally friendly synthesis of a 2H-indazole derivative via N–N bond coupling using the interaction of 2-azidobenzaldehyde and aniline in EtOH solvent. Constant Current electrosynthesis was performed in an undivided cell at ambient temperature with tetrabutylammonium hexafluorophosphate (Bu₄NPF₆) as a supporting electrolyte. The protocol's enticing qualities include clean synthesis, the use of electricity rather than chemical reagents, and atom economy.

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来源期刊

Journal of Heterocyclic Chemistry 化学-有机化学

CiteScore

5.20

自引率

4.20%

发文量

177

审稿时长

3.9 months

期刊介绍： The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.