{"title":"CEC02-02现行的(体内)神经毒性试验","authors":"P. Goldsteen","doi":"10.1016/j.toxlet.2025.07.016","DOIUrl":null,"url":null,"abstract":"<div><div>An overview will be given on the applicable guidelines and the implementation thereof in general toxicity and reproductive and developmental toxicity studies. The DNT endpoints and their methodology as well as the results they provide will be discussed, together with the challenges/limitations that are faced.</div></div>","PeriodicalId":23206,"journal":{"name":"Toxicology letters","volume":"411 ","pages":"Page S6"},"PeriodicalIF":2.9000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CEC02-02 Current regulatory (in vivo) neurotoxicity testing\",\"authors\":\"P. Goldsteen\",\"doi\":\"10.1016/j.toxlet.2025.07.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>An overview will be given on the applicable guidelines and the implementation thereof in general toxicity and reproductive and developmental toxicity studies. The DNT endpoints and their methodology as well as the results they provide will be discussed, together with the challenges/limitations that are faced.</div></div>\",\"PeriodicalId\":23206,\"journal\":{\"name\":\"Toxicology letters\",\"volume\":\"411 \",\"pages\":\"Page S6\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicology letters\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0378427425015991\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"TOXICOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicology letters","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0378427425015991","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"TOXICOLOGY","Score":null,"Total":0}
CEC02-02 Current regulatory (in vivo) neurotoxicity testing
An overview will be given on the applicable guidelines and the implementation thereof in general toxicity and reproductive and developmental toxicity studies. The DNT endpoints and their methodology as well as the results they provide will be discussed, together with the challenges/limitations that are faced.