Sandra Mallone, Andrea Tavilla, Tania Lopez, Daniela Pierannunzio, Luigino Dal Maso, Stefano Guzzinati, Ugo Fedeli, Alberto Gagliani, Alessandra Buja, Manuel Zorzi, Mario Fusco, Federica Toffolutti, Silvia Francisci
{"title":"确定意大利甲状腺和黑色素瘤癌症患者的医疗保健服务的间接方法:Epicost-2项目。","authors":"Sandra Mallone, Andrea Tavilla, Tania Lopez, Daniela Pierannunzio, Luigino Dal Maso, Stefano Guzzinati, Ugo Fedeli, Alberto Gagliani, Alessandra Buja, Manuel Zorzi, Mario Fusco, Federica Toffolutti, Silvia Francisci","doi":"10.1177/03008916251353109","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>An indirect approach was applied to the case-study of thyroid cancer (TC) and melanoma of the skin (MS) in Italy to identify health services (HS) for cancer patients and to enable cost estimation.</p><p><strong>Materials and methods: </strong>Within the Epicost-2 project, a self-controlled crossover design analysed TC and MS 2018 prevalent cases from Italian cancer registries. Controls (1:1) were matched to cases 18-6 months prior to diagnosis; increases between cases and controls in potentially cancer-related HS claims (P⩽5%) were identified.</p><p><strong>Validation: </strong>Oncology and clinical experts validated cancer-related HS lists using statistical, clinical, and economic criteria.</p><p><strong>Results: </strong>The approach identified 202 and 333 cancer-related HS codes for TC and MS, respectively, aligned with clinical pathways.</p><p><strong>Discussion: </strong>The indirect approach reduced validation workload by 75% versus direct one.</p><p><strong>Conclusion: </strong>The approach identifies the costs of cancer care that could also be reproduced in other countries with consistent results, and the approach applied to other cancers.</p>","PeriodicalId":23349,"journal":{"name":"Tumori","volume":" ","pages":"400-412"},"PeriodicalIF":3.1000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476483/pdf/","citationCount":"0","resultStr":"{\"title\":\"An indirect approach to identify the healthcare services for thyroid and melanoma cancer patients in Italy: Epicost-2 project.\",\"authors\":\"Sandra Mallone, Andrea Tavilla, Tania Lopez, Daniela Pierannunzio, Luigino Dal Maso, Stefano Guzzinati, Ugo Fedeli, Alberto Gagliani, Alessandra Buja, Manuel Zorzi, Mario Fusco, Federica Toffolutti, Silvia Francisci\",\"doi\":\"10.1177/03008916251353109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>An indirect approach was applied to the case-study of thyroid cancer (TC) and melanoma of the skin (MS) in Italy to identify health services (HS) for cancer patients and to enable cost estimation.</p><p><strong>Materials and methods: </strong>Within the Epicost-2 project, a self-controlled crossover design analysed TC and MS 2018 prevalent cases from Italian cancer registries. Controls (1:1) were matched to cases 18-6 months prior to diagnosis; increases between cases and controls in potentially cancer-related HS claims (P⩽5%) were identified.</p><p><strong>Validation: </strong>Oncology and clinical experts validated cancer-related HS lists using statistical, clinical, and economic criteria.</p><p><strong>Results: </strong>The approach identified 202 and 333 cancer-related HS codes for TC and MS, respectively, aligned with clinical pathways.</p><p><strong>Discussion: </strong>The indirect approach reduced validation workload by 75% versus direct one.</p><p><strong>Conclusion: </strong>The approach identifies the costs of cancer care that could also be reproduced in other countries with consistent results, and the approach applied to other cancers.</p>\",\"PeriodicalId\":23349,\"journal\":{\"name\":\"Tumori\",\"volume\":\" \",\"pages\":\"400-412\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476483/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tumori\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/03008916251353109\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tumori","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/03008916251353109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/4 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
An indirect approach to identify the healthcare services for thyroid and melanoma cancer patients in Italy: Epicost-2 project.
Introduction: An indirect approach was applied to the case-study of thyroid cancer (TC) and melanoma of the skin (MS) in Italy to identify health services (HS) for cancer patients and to enable cost estimation.
Materials and methods: Within the Epicost-2 project, a self-controlled crossover design analysed TC and MS 2018 prevalent cases from Italian cancer registries. Controls (1:1) were matched to cases 18-6 months prior to diagnosis; increases between cases and controls in potentially cancer-related HS claims (P⩽5%) were identified.
Validation: Oncology and clinical experts validated cancer-related HS lists using statistical, clinical, and economic criteria.
Results: The approach identified 202 and 333 cancer-related HS codes for TC and MS, respectively, aligned with clinical pathways.
Discussion: The indirect approach reduced validation workload by 75% versus direct one.
Conclusion: The approach identifies the costs of cancer care that could also be reproduced in other countries with consistent results, and the approach applied to other cancers.
期刊介绍:
Tumori Journal covers all aspects of cancer science and clinical practice with a strong focus on prevention, translational medicine and clinically relevant reports. We invite the publication of randomized trials and reports on large, consecutive patient series that investigate the real impact of new techniques, drugs and devices inday-to-day clinical practice.